Murali-group / Beeline

BEELINE: evaluation of algorithms for gene regulatory network inference
GNU General Public License v3.0
175 stars 53 forks source link

Analysis of network motifs #7

Closed sahasradude closed 5 years ago

sahasradude commented 5 years ago

Look for motifs specific to cell differentiation (like the one described in: "https://www.nature.com/articles/nature08533#gene-regulatory-networks-and-cell-fate-attractors"

amoghpj commented 5 years ago

@adyprat has currently implemented two motif-based analyses:

  1. The motif bias analysis as described in https://www.nature.com/articles/nmeth.2016, and
  2. A count of different network motifs in the predicted networks (feedback loop, feedforward loop, mutual interation, number of connected components in the top-k predicted edges.)