lookup result not accurate

NCATSTranslator / Feedback

A repo for tracking gaps in Translator data and finding ways to fill them.

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lookup result not accurate #763

Closed TranslatorIssueCreator closed 3 months ago

TranslatorIssueCreator commented 5 months ago

Type: Bug Report

URL: https://ui.test.transltr.io/main/results?l=Lepirudin&i=PUBCHEM.COMPOUND:118856773&t=4&r=0&q=9c30d7a5-be5f-4f44-a12e-376369954f57

ARS PK: 0951aef6-f1a0-4061-9a45-66a6d94767ef

Steps to reproduce:

What genes may be downregulated by:Lepirudin search for TNFSF4

Screenshots:

sandrine-muller-research commented 5 months ago

When looking at the lookup results, I am struggling with understanding what is reported here through Text mining API: VEGF is in bold which does not support the gene in the lookup TNFSF4. In the text reported, the closest match to TNFSF4 would be TNF-alpha although the gene name for TNF-alpha is TNF not TNFSF4 that maps to another protein. I have not investigated further but it looks to me we have 2 issues:

UI display with correct bolded words
Text mining incorrect gene mapping

gprice1129 commented 4 months ago

@sandrine-muller-research thanks for reporting this! There appears to be a bug in the UI that causes at least some of the problems here. We are working on it.

gprice1129 commented 3 months ago

@sandrine-muller-research we have verified the fix on Test. Going to close the issue but please re-open if you encounter the problem again.