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NCATSTranslator / Feedback

A repo for tracking gaps in Translator data and finding ways to fill them.
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thrombin and F2 should be normalized to a single node #764

Open TranslatorIssueCreator opened 6 months ago

TranslatorIssueCreator commented 6 months ago

Type: Bug Report

URL: https://ui.test.transltr.io/main/results?l=Bivalirudin&i=PUBCHEM.COMPOUND:16129704&t=4&r=0&q=e034c7d1-3f8e-473b-aceb-dbd9382fda7f

ARS PK: e034c7d1-3f8e-473b-aceb-dbd9382fda7f

Steps to reproduce:

What genes may be downregulated by:Bivalirudin? search for thrombin and F2

Screenshots:

sandrine-muller-research commented 6 months ago

F2 is the approved gene symbol for thrombin: https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/3535

sandrine-muller-research commented 6 months ago

same issue with UNIPROTKB:P00734

gaurav commented 2 months ago

I'm moving all protein/chemical conflation issues to Hammerhead.

sstemann commented 1 day ago

@gaurav this is not in Hammerhead, F2 and Thrombin are still two separate results

https://ui.test.transltr.io/results?l=Lepirudin&i=CHEBI:142437&t=4&r=0&q=126660c5-3da0-4c3f-94b5-dc096b1601f1

image

and in some cases, not all the thrombins are normalized https://ui.test.transltr.io/results?l=Bivalirudin&i=CHEBI:59173&t=4&r=0&q=c0504199-5f34-44ef-8489-7c53fcb3e453

image