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ChEBI role classification seems off #842

Closed khanspers closed 2 months ago

khanspers commented 2 months ago

What drugs may treat conditions related to seasonal allergic rhinitis?

https://ui.test.transltr.io/main/results?l=Seasonal%20Allergic%20Rhinitis&i=MONDO:0005324&t=0&r=0&q=6fff0b27-c22a-4b6b-982d-d8b03eb29421

Goserelin is classified as "anti-allergic agent" in the UI, using ChEBI role classification. I thought this was curious since Goserelin is a gonadotropin releasing hormone agonist. Looking at the ChEBI entry for Goserelin, the only ontology term listed is “organic molecular entity”: https://www.ebi.ac.uk/chebi/searchId.do?chebiId=5523

Also searched the ChEBI anti-allergic compounds list (https://www.ebi.ac.uk/chebi/chebiOntology.do?chebiId=50857) for CHEBI:5523; it's not present.

There are other results from the same query that are classified as anti-allergic that are also not on the list from ChEBI: Epanolol, Acebutolol, Atazoline…..

sstemann commented 2 months ago

@gprice1129 @dnsmith124 my first thought is that this was some sort of annotation server down malfunction but i replicated the same test today and am seeing Goserline as an anti-allergic agent just like Kristina reported. It doesnt look fleeting. I don't see this annotation in the annotation server entry for CHEBI:5523. Can you please let us know what's going on here?

https://ui.test.transltr.io/main/results?l=Seasonal%20Allergic%20Rhinitis&i=MONDO:0005324&t=0&r=0&q=133c7ae3-6bdc-4769-a758-2db8ea79d99c

https://biothings.ncats.io/annotator/CHEBI:5523

Genomewide commented 2 months ago

@gprice1129 remind me of the process when an ID is matched related to displaying the term or the parent of the term.

gprice1129 commented 2 months ago

Thanks for pointing this out! This is a bug in the current faceting system that I will work on fixing right away.

gprice1129 commented 2 months ago

The fix for this is now in Test. I confirmed that the reported issue no longer happens. Going to close.