NCATSTranslator / Feedback

A repo for tracking gaps in Translator data and finding ways to fill them.
7 stars 0 forks source link

what genes' activity may be decreased does not have the same edges as the same query for chemicals by gene #843

Open sstemann opened 4 months ago

sstemann commented 4 months ago

I was reviewing #800 and in testing, tested queries:

What genes' activity may be decreased by:[Semaglutide]: https://ui.test.transltr.io/main/results?l=Semaglutide&i=CHEBI:167574&t=4&r=0&q=de790a66-3a75-4307-8654-8c06e8cdb44a

What chemicals may decrease the activity of:[GCG (Human)]: https://ui.test.transltr.io/main/results?l=GCG%20(Human)&i=NCBIGene:2641&t=2&r=0&q=179f83d1-a07e-4163-8ffa-d8efb15b1b76

It seems a bit strange to me, that we have many more paths and Evidence for the first direction, and then the same relationship the other way, has much less of both. In the What genes' activity may be decreased, we see responses from ARAGORN, BTE and Unsecret, so I'm posing this question regarding why are they don't respond when the question is asked the other way.

image

sstemann commented 3 months ago

originally noted in #247