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A repo for tracking gaps in Translator data and finding ways to fill them.
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"Inferred" Edges from CTD, DrugCentral, SIDER, ChEMBL, DrugCentral #927

Open sstemann opened 2 months ago

sstemann commented 2 months ago

To recreate in Test or Prod (with Fugu) run MVP1 > Breast Cancer. The question here is - do inferred edges come from Primary Knowledge Sources?

Test: https://ui.test.transltr.io/results?l=Breast%20Cancer&i=MONDO:0007254&t=0&r=0&q=c395561b-8d82-4682-954f-99a7d08b0ecc Prod: https://ui.transltr.io/results?l=Breast%20Cancer&i=MONDO:0007254&t=0&r=0&q=5b4ce30a-b1ae-4c82-9e33-9e1881ae3d75

The clearest example is ONO-8711 (from ARAGORN) it only has Inferred Paths image

and the EPC on the top level path is a Pub, and CTD - at a minimum it looks like its missing the ARAGORN EPC image

VIa the ARAX GUI it looks like its got the same Pub and CTD on both the inferred edge and the support graph edge image

image

Another example is Raloxifene it's inferred Treats edge lists BTE and SIDER - however ARAGORN is the only ARA to list SIDER on the Inferred Edge: image

And here's Sacituzumab Govitecan with inferred edges from BTE, ChEMBL, DrugCentral and Service Provide TRAPI endpoints. After checking all other ARAs, ARAGORN is the only one listing primary KSs on their inferred edge.

image