Asset 264: Talcid as an answer

[colleenXu]

This asset currently uses PUBCHEM.COMPOUND:56842000 as the expected answer ID for Talcid.

I'm going to assume that the intention is to find hydrotalcite, the active ingredient of Talcid. It's kinda confusing because Talcid may be a brand drug name only used in specific countries.

I think there's several issues with this test:

• this doesn't appear to be a drug sold in the US, which may mean there's less annotation for it.
• hydrotalcite is a mixture of aluminium/magnesium/carbonate/hydroxide. However, the individual compounds may be annotated more. For example, while I don't see hydrotalcite in BTE's result sets, I see the following individual compounds:
  • magnesium hydroxide (rank 37)
  • aluminum carbonate
  • magnesium carbonate
  • DIHYDROXIALUMINI SODIUM CARBONATE
• there's a different NodeNorm entity for hydrotalcite with more IDs mapped to it: PUBCHEM.COMPOUND:73415812

Should this test look for the individual compounds instead? Or use the different ID (NodeNorm issue)?

[colleenXu]

Related to other issues:

• https://github.com/NCATSTranslator/Tests/issues/62?
• I think all tools have been consistently failing this test, which may be in part due to issues with this answer:
  • https://github.com/NCATSTranslator/Tests/issues/69
  • https://github.com/NCATSTranslator/Tests/issues/32