NCI-Thesaurus / thesaurus-obo-edition

OBO Library edition of NCIt
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astrocytoma vs astrocytic tumor #23

Closed cmungall closed 6 years ago

cmungall commented 6 years ago

NCIT appears to formally treat astrocytes and GBM as distinct, with an astrocytic tumor unifying them.

To the casual user of NCIT the difference of these may not be apparent. Many other resources - rightly or wrongly - use the term astrocyte as the parent class here

The definitions are very similar (identical in the core part, before the .):

Diffing the text we can see that the former includes glioblastoma

I suggest making the difference more obvious to avoid the casual user selecting 'astrocytoma' when they actually mean 'astrocytic tumor'. I'm not sure how best to do this. An rdfs:comment with a note here? In OBO we have properties such as 'editor note' and 'curator note' and in ontologies such as GO we also include comments for curators and users where the terminology can be ambiguous, to avoid annotation errors.

cmungall commented 6 years ago

As an example of what is possibly more colloquial usage, ORDO has:

image

The high grade astrocytoma classification corresponds to HG astrocytic tumor in NCIT

NCIEVS commented 6 years ago

The editing group has added a design note:

"Glioblastoma is not an astrocytoma. It is an astrocytic tumor. The latter includes astrocytomas and glioblastomas. However, when an anaplastic astrocytoma progresses to grade IV tumor, it is called a glioblastoma."