search

NIEHS / RGCA

Reflected Generalized Concentration Addition approach for prediction of combined chemical mixtures responses. See `citation` for appropriate citation in using this package.
https://niehs.github.io/RGCA/
0 stars 0 forks source link

Define Key Functions in RGCA #14

Closed kyle-messier closed 4 months ago

kyle-messier commented 5 months ago
  1. Dose-Response Functions (some replication of tcpl)
  2. Inverse D-R functions
  3. Nimble MCMC wrapper: Given replicate samples, dose-response data as a df, fit the individual d-r RE model
  4. GCA and RGCA mixture fitting: fit the mixture, default as random or all the same, [out-source the clustering]
kyle-messier commented 5 months ago

TARGETS

Given the key functions, separating the following into the user side or targets pipeline

  1. Create inst/ folder
  2. _targets.R etc. lives in inst/targets/
  3. Demonstrate the pipeline from the manuscript including different clustering within targets pipeline.

dzilber commented 4 months ago

Functions that are just for supporting the manuscript, such as plotting and reading Tox21 data, have been moved to the inst folder. The manuscript vignette has been converted into an article and is not built as part of the package, so the extra imports like ggplot2 and cowplot are not needed for the package and have been removed.