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NU-QDSC / cancer-informatics

Repository to track cancer informatics best practices and shared code.
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number of patients who received immunotherapy #347

Closed PerifanosPrometheus closed 1 week ago

PerifanosPrometheus commented 3 months ago

https://jira.fsm.northwestern.edu/browse/RW-5488

mgurley commented 2 months ago

Hi Giorgio,

I am wondering if you can query additional data for this request. Built on the cohort of immunotherapy data I requested last time, can you also identify endocrine diseases based on ICD codes and corresponding medication and lab values (see list below)? With these data, I plan to generate some summary statistics as preliminary data for R01 resubmission. I have not decided how to summarize the data. At this point, I am just wondering if there are med and lab data in our EDW?

Thanks, Lili

ICD 9/10 (Endocrine disease, no type I diabetes ) (no code before ICI, date >ICI) Hypothyroidism: E03; 244 Hyperthyroidism: E05; 242 Thyroiditis : E06; 245 Adrenal Insufficiency: E27; 255 Hypophysitis: E23 medication Synthroid, levothyroxine, Lovoxyl,Armour, Thyrolar, Liotrix, Cytomel, Liothyronine Sodium, Unithroid, L-Thyroxin, Levo-T, Levoxyl, Novothyrox, Levothroid, Levolet, and Triostat, hydrocortisone, dexamethasone, prednisone, glucocorticoids, methimazole or Propylthiouracil

  1. abnormal lab values -TSH and T4/T3 for hypo, hyper, adrenal insufficiency, hypothysitis TSH (Thyroid Stimulating Hormone):LOINC: 3016-3 Free T4 (Thyroxine, Free):LOINC: 3024-7 Total T4 (Thyroxine, Total):LOINC: 3026-2 Free T3 (Triiodothyronine, Free):LOINC: 3052-2 Total T3 (Triiodothyronine, Total):LOINC: 3054-8 cortisol and ACTH for Adrenal insufficiency and hypothysitis Cortisol: LOINC: 2143-6 (serum or plasma) ACTH (Adrenocorticotropic Hormone):LOINC: 2141-0
PerifanosPrometheus commented 1 week ago

Completed