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NaegleLab / CoDIAC

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Incorrect arrangement of domains in Uniprot reference file #52

Closed alekhyaa2 closed 1 month ago

alekhyaa2 commented 1 month ago

Is your feature request related to a problem? Please describe. The uniprot reference file created includes Interpro domains column. The domains extracted from interpro are not in the right order based on their domain ranges. For example, GRAP2 - Interpro domains are SH3_domain:IPR001452:1:56;SH3_domain:IPR001452:271:330;SH2:IPR000980:56:149. The sh2 domain should be in between the two sh3 domains but the order is rearranged. Similarly found this issue with VAV1. This is important for downstream analysis that uses this reference file for feature generation.

knaegle commented 1 month ago

Fixed this, it is done at the time of return from InterPro module, these now come back in the order by start site.