Closed patrickjdanaher closed 1 week ago
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Idea: can we use cells' neighborhoods to estimate the background they're getting from segmentation errors?
step 1: use each cell's neighbors to estimate the 'background' from segmentation errors that it's subject to step 2: expand the "bg" argument to take matrix values? (but this would be dense. ouch.)
...would this work? Seems like minor seg errors don't impact cell typing, and major errors would be insufficiently addressed by this method.