Spectral library unknown error

[ihorrible]

Hi everyone!

Version info:

FragPipe version 17.1 MSFragger version 3.4 Philosopher version 4.1.1 (build 1637179075)

I am trying to generate a spectral library for DDA based on d.files from Bruker Tims TOF:

• first time I run as a user and I have error access denied (see file attached);
• second time I run MS Fragger as an administrator and I have an unknown error (see file attached).

Traceback (most recent call last): File "C:\Users\iataraskin\Desktop\Projects\MIPT\Thesis\FragPipe-jre-17.1\fragpipe\tools\speclib\gen_con_spec_lib.py", line 965, in main_easypqp() File "C:\Users\iataraskin\Desktop\Projects\MIPT\Thesis\FragPipe-jre-17.1\fragpipe\tools\speclib\gen_con_spec_lib.py", line 768, in main_easypqp subprocess.run([os.fspath(easypqp), '--version'], check=True) File "C:\Users\iataraskin\Anaconda3\lib\subprocess.py", line 512, in run raise CalledProcessError(retcode, process.args, subprocess.CalledProcessError: Command '['C:\Users\iataraskin\Anaconda3\Scripts\easypqp.exe', '--version']' returned non-zero exit status 1. Process 'SpecLibGen' finished, exit code: 1 Process returned non-zero exit code, stopping

Cancelling 2 remaining tasks

I have selected a default workflow on a workflow tab. It seems to me like a problem with easypqp library installed in python, but everything looks OK on a config tab where it shows that easypqp 0.1.26 and no problem (see also file attached)
![ok](https://user-images.githubusercontent.com/63013549/152727067-5fd75c30-ff40-4596-9695-eaba6201f10c.PNG)
. 

Could please help me with this error and what should I change in order to fix it? 

Thanks,

Ivan 

![permission error](https://user-images.githubusercontent.com/63013549/152726710-8a67098a-2515-4503-acd0-254b2517bd42.PNG)
![unknown errror_spectral library](https://user-images.githubusercontent.com/63013549/152726713-918d11f5-193a-468b-bd92-375befe3811f.PNG)

[log_2022-02-07_07-47-33.txt](https://github.com/Nesvilab/FragPipe/files/8012408/log_2022-02-07_07-47-33.txt)
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[guoci]

@ihorrible Can you run the following command line and show me the output? C:\Users\iataraskin\Anaconda3\Scripts\easypqp.exe --version

[ihorrible]

@ihorrible Can you run the following command line and show me the output? C:\Users\iataraskin\Anaconda3\Scripts\easypqp.exe --version

It is stated that access is denied. Any guess what I should do to unblock this?

[guoci]

@ihorrible can you click on the "Install/Upgrade EasyPQP and try again?

[ihorrible]

the problem was with access rights on my laptop. now everything works OK. thank you !