Example 01 shows how to fit a mutation catalogue to the COSMIC 30 reference signatures. Could an example be added of fitting using one of the PCAWG tissue-specific signatures and back-transforming it into the biologically-annotated COSMIC signatures?
Example 01 shows how to fit a mutation catalogue to the COSMIC 30 reference signatures. Could an example be added of fitting using one of the PCAWG tissue-specific signatures and back-transforming it into the biologically-annotated COSMIC signatures?