search

NotaCS / Functionnectome

Project your functional brain signal onto the white matter, and explore the pathways supporting brain functions.
Other
22 stars 4 forks source link

[question] Voxel-wise mask recommendation for whole brain analysis #5

Closed smeisler closed 2 years ago

smeisler commented 2 years ago

Hi,

I am planning on running a whole brain voxel-based analysis of Functionnectome outputs; should I use the whole-brain mask, or a gray-matter mask? Would using a whole-brain mask lead to redundancy and longer running times, or would I be missing something important by restricting only to gray-matter?

Thanks, Steven

EDIT: see in the manual that it should be gray matter

NotaCS commented 2 years ago

Hi Steven,

Yes, as you saw, we recommend using a grey matter mask. Indeed, it defines what kind of signal is projected onto the white matter, so if you use the whole brain, you'll get the white matter BOLD signal used there. Although there are some works exploring this white matter signal, it's much noisier than the grey matter's so we prefer not to keep it.

Cheers, Victor