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Lack of instruction in the Chapter Hepatic impairment in learning center #1499

Closed FishinW closed 1 year ago

FishinW commented 1 year ago

I follow the instruction of the Chapter Hepatic impairment and I found some processes are not mentioned. The expression files of CYP1A2 and CYP3A4 were built after the individual files were built, but there is no content about adjust the CYP expression profile. All individual files were cloned based on the control files, which means that the expression of CYP1A2 and 3A4 was the control file. nfmwj1er

Yuri05 commented 1 year ago

@stephanschaller

StephanSchaller commented 1 year ago

@FishinW , are you referring to the exercise in the esqLABS learning center?

Ecercise "Hepatic Impairment" describes here (Section "Expression Profile: Child-Pugh A, B and C") how to adapt the reference concentration: image

StephanSchaller commented 1 year ago

@Yuri05 , can you move this to the forum?