Opening V11 PK-Sim project in PK-Sim and sending a simulation to MoBi does not properly work

Open-Systems-Pharmacology / MoBi

MoBi® is a software tool for multiscale physiological modeling and simulation

Other

28 stars 9 forks source link

Open PavelBal opened 3 months ago

PavelBal commented 3 months ago

Open the Midazolam project from here https://github.com/Open-Systems-Pharmacology/OSP-PBPK-Model-Library/tree/master/Midazolam in PK-Sim 12
Send the simulation "iv 0.05 mg/kg (2 min)" to MoBi
Create a new simulation from the existing building blocs
Try to run the simulation:
Compare simulations: there are tons of differences. How can this be?

E.g. Organism|Volume (plasma) is defined as a sum formula in the building block but not in the simulation! Where are expression values stored?

Yuri05 commented 3 months ago

Unit conversion issue probably

PavelBal commented 3 months ago

No, there are just many parameters that are in the simulation and not in the building blocks. E.g. "Weight" is not defined etc..

Yuri05 commented 3 months ago

Actually what I meant was "Project conversion issue" 😄