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Open-Systems-Pharmacology / PK-Sim

PK-Sim® is a comprehensive software tool for whole-body physiologically based pharmacokinetic modeling
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Parmaeter changed by disease state algorithm should be marked as IsChangedByCreateIndividual (or at least added to the list of changed parmaeters when creatinga population) #2016

Closed msevestre closed 2 years ago

msevestre commented 2 years ago

as a reference beforfe the change 146 parameters

ROOT|Organism|Weight
ROOT|Organism|BMI
ROOT|Organism|BSA
ROOT|Organism|Age
ROOT|Organism|Gestational age
ROOT|Organism|Height
ROOT|Organism|Ontogeny factor (albumin)
ROOT|Organism|Ontogeny factor (alpha1-acid glycoprotein)
ROOT|Organism|Hematocrit
ROOT|Organism|MeanBW
ROOT|Organism|MeanHeight
ROOT|Organism|VenousBlood|Volume
ROOT|Organism|ArterialBlood|Volume
ROOT|Organism|Bone|Blood flow rate
ROOT|Organism|Bone|Specific blood flow rate
ROOT|Organism|Bone|Volume
ROOT|Organism|Brain|Blood flow rate
ROOT|Organism|Brain|Volume
ROOT|Organism|Brain|Specific blood flow rate
ROOT|Organism|Fat|Fraction intracellular
ROOT|Organism|Fat|Blood flow rate
ROOT|Organism|Fat|Volume
ROOT|Organism|Fat|Vf (lipid)
ROOT|Organism|Fat|Vf (neutral lipid)-PT
ROOT|Organism|Fat|Vf (phospholipid)-PT
ROOT|Organism|Fat|Fraction interstitial
ROOT|Organism|Fat|Vf (water)
ROOT|Organism|Fat|Vf (water)-PT
ROOT|Organism|Fat|Vf (neutral lipid)-RR
ROOT|Organism|Fat|Vf (neutral lipid)-WS
ROOT|Organism|Fat|Vf (neutral phospholipid)-RR
ROOT|Organism|Fat|Vf (neutral phospholipid, plasma)-WS
ROOT|Organism|Fat|Vf (extracellular water)-RR
ROOT|Organism|Fat|Vf (intracellular water)-RR
ROOT|Organism|Fat|Vf (water)-WS
ROOT|Organism|Fat|Specific blood flow rate
ROOT|Organism|Gonads|Blood flow rate
ROOT|Organism|Gonads|Volume
ROOT|Organism|Gonads|Specific blood flow rate
ROOT|Organism|Heart|Blood flow rate
ROOT|Organism|Heart|Volume
ROOT|Organism|Heart|Specific blood flow rate
ROOT|Organism|Kidney|GFR (specific)
ROOT|Organism|Kidney|eGFR
ROOT|Organism|Kidney|Blood flow rate
ROOT|Organism|Kidney|Volume
ROOT|Organism|Kidney|Age of aging onset
ROOT|Organism|Kidney|Aging half-time
ROOT|Organism|Kidney|GFRmat
ROOT|Organism|Kidney|Hill coefficient for aging GFR
ROOT|Organism|Kidney|Hill coefficient for GFR
ROOT|Organism|Kidney|Maximal decreasing rate factor
ROOT|Organism|Kidney|TM50 for GFR
ROOT|Organism|Kidney|Specific blood flow rate
ROOT|Organism|Lumen|Effective surface area variability factor
ROOT|Organism|Lumen|Stomach|Distal radius
ROOT|Organism|Lumen|Stomach|Gastric emptying time
ROOT|Organism|Lumen|Stomach|GET_alpha (Weibull function) variability factor
ROOT|Organism|Lumen|Stomach|GET_beta (Weibull function) variability factor
ROOT|Organism|Lumen|Stomach|Length
ROOT|Organism|Lumen|Stomach|Proximal radius
ROOT|Organism|Lumen|Duodenum|Effective surface area enhancement factor
ROOT|Organism|Lumen|UpperJejunum|Effective surface area enhancement factor
ROOT|Organism|Lumen|LowerJejunum|Effective surface area enhancement factor
ROOT|Organism|Lumen|UpperIleum|Effective surface area enhancement factor
ROOT|Organism|Lumen|LowerIleum|Effective surface area enhancement factor
ROOT|Organism|Lumen|Caecum|Effective surface area enhancement factor
ROOT|Organism|Lumen|ColonAscendens|Effective surface area enhancement factor
ROOT|Organism|Lumen|ColonTransversum|Effective surface area enhancement factor
ROOT|Organism|Lumen|ColonDescendens|Effective surface area enhancement factor
ROOT|Organism|Lumen|ColonSigmoid|Effective surface area enhancement factor
ROOT|Organism|Lumen|Rectum|Effective surface area enhancement factor
ROOT|Organism|Stomach|Blood flow rate
ROOT|Organism|Stomach|Volume
ROOT|Organism|Stomach|Specific blood flow rate
ROOT|Organism|SmallIntestine|Blood flow rate
ROOT|Organism|SmallIntestine|Small intestinal transit time
ROOT|Organism|SmallIntestine|Volume
ROOT|Organism|SmallIntestine|Specific blood flow rate
ROOT|Organism|SmallIntestine|Mucosa|Duodenum|Volume
ROOT|Organism|SmallIntestine|Mucosa|Duodenum|Blood flow rate
ROOT|Organism|SmallIntestine|Mucosa|UpperJejunum|Volume
ROOT|Organism|SmallIntestine|Mucosa|UpperJejunum|Blood flow rate
ROOT|Organism|SmallIntestine|Mucosa|LowerJejunum|Volume
ROOT|Organism|SmallIntestine|Mucosa|LowerJejunum|Blood flow rate
ROOT|Organism|SmallIntestine|Mucosa|UpperIleum|Volume
ROOT|Organism|SmallIntestine|Mucosa|UpperIleum|Blood flow rate
ROOT|Organism|SmallIntestine|Mucosa|LowerIleum|Volume
ROOT|Organism|SmallIntestine|Mucosa|LowerIleum|Blood flow rate
ROOT|Organism|LargeIntestine|Blood flow rate
ROOT|Organism|LargeIntestine|Large intestinal transit time
ROOT|Organism|LargeIntestine|Volume
ROOT|Organism|LargeIntestine|Specific blood flow rate
ROOT|Organism|LargeIntestine|Mucosa|Caecum|Volume
ROOT|Organism|LargeIntestine|Mucosa|Caecum|Blood flow rate
ROOT|Organism|LargeIntestine|Mucosa|ColonAscendens|Volume
ROOT|Organism|LargeIntestine|Mucosa|ColonAscendens|Blood flow rate
ROOT|Organism|LargeIntestine|Mucosa|ColonTransversum|Volume
ROOT|Organism|LargeIntestine|Mucosa|ColonTransversum|Blood flow rate
ROOT|Organism|LargeIntestine|Mucosa|ColonDescendens|Volume
ROOT|Organism|LargeIntestine|Mucosa|ColonDescendens|Blood flow rate
ROOT|Organism|LargeIntestine|Mucosa|ColonSigmoid|Volume
ROOT|Organism|LargeIntestine|Mucosa|ColonSigmoid|Blood flow rate
ROOT|Organism|LargeIntestine|Mucosa|Rectum|Volume
ROOT|Organism|LargeIntestine|Mucosa|Rectum|Blood flow rate
ROOT|Organism|Liver|Blood flow rate
ROOT|Organism|Liver|Volume
ROOT|Organism|Liver|Specific blood flow rate
ROOT|Organism|Liver|Periportal|Volume
ROOT|Organism|Liver|Periportal|Blood flow rate
ROOT|Organism|Liver|Pericentral|Volume
ROOT|Organism|Liver|Pericentral|Blood flow rate
ROOT|Organism|Lung|Blood flow rate
ROOT|Organism|Lung|Volume
ROOT|Organism|Lung|Fraction vascular
ROOT|Organism|Muscle|Fraction intracellular
ROOT|Organism|Muscle|Blood flow rate
ROOT|Organism|Muscle|Volume
ROOT|Organism|Muscle|Vf (lipid)
ROOT|Organism|Muscle|Vf (neutral lipid)-PT
ROOT|Organism|Muscle|Vf (phospholipid)-PT
ROOT|Organism|Muscle|Vf (protein)
ROOT|Organism|Muscle|Vf (water)
ROOT|Organism|Muscle|Vf (water)-PT
ROOT|Organism|Muscle|Fraction interstitial
ROOT|Organism|Muscle|Vf (neutral lipid)-RR
ROOT|Organism|Muscle|Vf (neutral lipid)-WS
ROOT|Organism|Muscle|Vf (neutral phospholipid)-RR
ROOT|Organism|Muscle|Vf (neutral phospholipid, plasma)-WS
ROOT|Organism|Muscle|Vf (extracellular water)-RR
ROOT|Organism|Muscle|Vf (protein)-WS
ROOT|Organism|Muscle|Vf (intracellular water)-RR
ROOT|Organism|Muscle|Vf (water)-WS
ROOT|Organism|Muscle|Specific blood flow rate
ROOT|Organism|Pancreas|Blood flow rate
ROOT|Organism|Pancreas|Volume
ROOT|Organism|Pancreas|Specific blood flow rate
ROOT|Organism|PortalVein|Blood flow rate
ROOT|Organism|PortalVein|Volume
ROOT|Organism|Skin|Blood flow rate
ROOT|Organism|Skin|Volume
ROOT|Organism|Skin|Specific blood flow rate
ROOT|Organism|Spleen|Blood flow rate
ROOT|Organism|Spleen|Volume
ROOT|Organism|Spleen|Specific blood flow rate
ROOT|Organism|Saliva|Volume