search

Open-Systems-Pharmacology / QualificationRunner

Qualification runner in charge of managing a qualification workflow
Other
0 stars 1 forks source link

Fixes #105 only export sim used #106

Closed msevestre closed 2 years ago

msevestre commented 2 years ago

running the advanced examples, I am getting this

info: QualificationRunner[0] Starting qualification workflow info: QualificationRunner[0] Starting validation runs... info: QualificationRunner[0] Starting qualification runs... fail: QualificationRunner[0] Project configuration for 'Midazolam' is invalid. Please check the log file at 'C:\tests\v11\QualiTest\temp\Midazolam\log.txt' for details. Project configuration for 'Itraconazole' is invalid. Please check the log file at 'C:\tests\v11\QualiTest\temp\Itraconazole\log.txt' for details. Project configuration for 'Midazolam_Itraconazole_DDI' is invalid. Please check the log file at 'C:\tests\v11\QualiTest\temp\Midazolam_Itraconazole_DDI\log.txt' for details. fail: QualificationRunner[0] Qualification Workflow failed

but the log has nothing... so I am not sure what's going on. I'll investigate

msevestre commented 2 years ago

this is the log for Midazolam

[2022-02-02 18:26:32.935 PK-Sim INFORMATION] Starting validation run... 
 [2022-02-02 18:26:33.702 Midazolam INFORMATION] Validation run terminated for Midazolam 
 [2022-02-02 18:26:38.227 PK-Sim INFORMATION] Starting qualification run... 
 [2022-02-02 18:26:42.865 PK-Sim WARNING] Snapshot parameter 'Ontogeny factor GI' was not found in 'CYP3A4'. 
 [2022-02-02 18:26:43.776 PK-Sim WARNING] Snapshot parameter 'Ontogeny factor GI' was not found in 'ABCB1'. 
 [2022-02-02 18:26:43.777 PK-Sim WARNING] Snapshot parameter 'Ontogeny factor' was not found in 'ABCB1'. 
 [2022-02-02 18:26:43.807 PK-Sim WARNING] Snapshot parameter 'Ontogeny factor GI' was not found in 'CYP3A4'. 
 [2022-02-02 18:26:43.807 PK-Sim WARNING] Snapshot parameter 'Ontogeny factor' was not found in 'CYP3A4'. 
 [2022-02-02 18:26:43.854 PK-Sim WARNING] Snapshot parameter 'Ontogeny factor GI' was not found in 'AADAC'. 
 [2022-02-02 18:26:43.856 PK-Sim WARNING] Snapshot parameter 'Ontogeny factor' was not found in 'AADAC'. 
 [2022-02-02 18:26:43.885 PK-Sim WARNING] Snapshot parameter 'Ontogeny factor GI' was not found in 'OATP1B1'. 
 [2022-02-02 18:26:43.886 PK-Sim WARNING] Snapshot parameter 'Ontogeny factor' was not found in 'OATP1B1'. 
 [2022-02-02 18:26:43.927 PK-Sim WARNING] Snapshot parameter 'Ontogeny factor GI' was not found in 'ATP1A2'. 
 [2022-02-02 18:26:43.928 PK-Sim WARNING] Snapshot parameter 'Ontogeny factor' was not found in 'ATP1A2'. 
 [2022-02-02 18:26:43.932 PK-Sim WARNING] ExpressionProfile named 'ABCB1|Human|European (P-gp modified, CYP3A4 36 h)' already exists in project.

I don't like some of those warnings..

Yuri05 commented 2 years ago

@msevestre Which qualification plan are you using? Maybe there are some parameters whose paths changed in V11?

msevestre commented 2 years ago

This is the qualifications run in pksim itself....I suspect some conversions issues

Running the advanced example from the qualification plan repo