OpenBEL / converter-reactome_to_bel

Convert Reactome to BEL
Apache License 2.0
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optionally treat has candidate from reactome as hasMember in BEL #2

Open tythomson opened 8 years ago

tythomson commented 8 years ago

has candiadate is used in reactome to represent putative family or set relationships, ie it is essentially a putative hasmember relationship. These are currently represented with hasComponent relationships in BEL, but should instead be represented with hasMember relationships. Perhaps this could be an optional flag so the user could choose whether or not to include putative relationships (and the fact that it is a putative relationships could be documented in the evidence?).

Example: http://www.reactome.org/PathwayBrowser/#/R-HSA-163685&SEL=R-HSA-163689&PATH=R-HSA-1430728 The catalyst for this reaction has a component that is "PP2A-catalytic subunit C" which has two candidate members. This is currently interpreted as a complex of these two proteins.

Note that this is related to Issue #1.