OpenChrom / openchrom

Visualization and Analysis of mass spectrometric and chromatographic data.
https://www.openchrom.net
Eclipse Public License 1.0
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Suggestion: plugin (file converter): import of Thermo Scientific orbitrap .raw files #529

Open LouisPM opened 2 months ago

LouisPM commented 2 months ago

Dear OpenChrom developers,

OpenChrom appears to be unable to open .raw files that have been created with Thermo Scientific LC-MS/MS mass spectrometers utilizing orbitrap mass analyzers.

A while ago, Thermo had released binaries that allow the conversion of these .raw files into .mzML files. And Hulstaert et al. (2019; Journal of Proteome Research) have published a wrapper that uses the mono implementation of Microsoft's .NET Framework (is a dependency) for cross-platform execution of this file parser. The project is available on GitHub: ThermoRawFileParser

As OpenChrom supports .mzML files, I was wondering whether one could implement a plugin for Thermo orbitrap .raw files simply by using above-mentioned ThermoRawFileParser to create a temporary .mzML file and subsequently open this one with the application?