Convert Drosophila motoneuron model to NeuroML2

[pgleeson]

Brief description

A model of a drosophila motoneuron is available on OSB in XPP (and other fomats): http://www.opensourcebrain.org/projects/drosophila-acc-l3-motoneuron-gunay-et-al-2014 The XPP version of this model can be converted to NeuroML2

Expected result

This model: https://github.com/cengique/drosophila-aCC-L3-motoneuron-model/blob/master/xpp-models/isopotential.ode is a self contained XPP model with one compartment & 3 active conductances. Run in XPP (install xpp & type keys: i g w f) it produces:

The cell model can be converted to NeuroML. This model could be used as the basis for the cell & channels & running the simulation.

Suggested steps

Read LEMS/NML2 paper.

Fork the project on GitHub.

Install XPP & test model locally

Update/add comments to the xpp code to gain understanding of behaviour

Create an initial LEMS file and cell & channel files based on the example above.

Adjust the parameters to match the behaviour of the XPP model.

Knowledge prerequisites

Experience with compartmental modelling

To be learned

NeuroML2 & LEMS

Mentor

Contact p.gleeson at ucl.ac.uk if you are interested in contributing to this task

[cengique]

Hey this is nice! I'll keep it on my desk for potential student projects.

Thanks, Padraig!

[pgleeson]

In progress by @jrieke and @borismarin. Follow progress with this project here: https://github.com/cengique/drosophila-aCC-L3-motoneuron-model/issues