Student recruitment in Edinburgh for October 2014

[PatrickThomson]

Hi Folks,

The University of Edinburgh are happy to let me have another student this year and I've been given the opportunity to recruit from students who've come from a year-long placement in an industrial research laboratory (they may even be canny enough to find this thread before applying (hi there!)). Are there any feedback or suggestions about the following document as a recruitment tool? I'm limited to that font size (12) and page count (1) so it might seem a little slim but e.g. I could cut out some references.

I've kept it at series 1 & 3 chemistry as representative rather than going into details, as IMO the available space is best used to sell the concept and idea. I'll be displayed alongside other organic projects in the areas of reaction development, catalysis, supramolecular, and some bio-organic work, but there are (afaik) no other medicinal projects, or not very many.

PDF: https://drive.google.com/file/d/0B6rAjqmPhHy5Uk1ySU1FY0czdGc/edit?usp=sharing

Google doc: https://docs.google.com/document/d/1vd164oVipnZ3AaaXjG7aCpeM4AnRlnJcQpFKN5Tc1og/edit

[mattodd]

Sorry for the delay, Patrick - was transitioning to Boston. This is really great news, well done. I hope someone picks up on this fantastic opportunity. My only advice on the document, if I'm not too late, would be to highlight the differences between actives and inactives. i.e. show for both series the active compound next to the inactive, to highlight the tantalisingly small differences. I'd also mention that the student would be working with collaborators worldwide, not just with Australian guys. And small typo "publicly". I think you're right to focus on Series 1 and 4. We have to wrap up Series 1 in the short term - if the student starts over the coming month or so there may be time to include. If it's after that, we should aim to wrap up Series 3. New data on Series 3 just came through: http://malaria.ourexperiment.org/biological_data/10252. Just can't seem to improve on OSM-S-106, so we totally need those twisted compounds, and the one or two others we prioritised, before we publish.

[PatrickThomson]

Yes, I should have said - the document's not going in until July, and the student won't start until October.

[PatrickThomson]

Ok, I put in my own Series 1 effort for purely egotistical reasons and because it's a really nice example of a tight SAR, and an example from the series 4 briefing document; I picked two that eyeball similarly (even though the conformation and HBA/HBD are very different) but have very different efficacy; I'm not explicitly fishing for a student that can usefully criticise a surface reading of the data but it'd be nice to be challenged on it - I'll probably learn more medchem than they'll learn synthesis.

My personal deadline is 7 days from now (18th July), so feedback is still useful!

Draft 2 PDF: https://drive.google.com/file/d/0B6rAjqmPhHy5TlhSWUFoNEs5QUE/edit?usp=sharing

Draft 2 DOC: https://drive.google.com/file/d/0B6rAjqmPhHy5TmF5Y08wWEpYMFE/edit?usp=sharing

[mattodd]

Looks good!

[PatrickThomson]

Ok, I've submitted this into our administrative section - here's hoping for a lot of interest again this year!

[pluralise]

Hi all, perhaps the students of the online drug discovery postgrad course run at Edinburgh university could also get involved with the OSM project in some way.

Course details here:

http://www.ed.ac.uk/schools-departments/biology/postgraduate/taught-programmes/online-programmes-drug-discovery

On Friday, July 18, 2014, PatrickThomson notifications@github.com wrote:

Closed #217 https://github.com/OpenSourceMalaria/OSM_To_Do_List/issues/217.

— Reply to this email directly or view it on GitHub https://github.com/OpenSourceMalaria/OSM_To_Do_List/issues/217#event-143193082 .