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OpenSourceMalaria / Series3

Everything to do with Open Source Malaria Series 3
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Installation of Furan Analog in DCNYS Page #10

Closed mattodd closed 5 years ago

mattodd commented 5 years ago

@mbhebhe We need to get the furan analog target installed on the DCNYS page, up top, since it's being actively pursued. Can you look at the corresponding S4 page for what's needed and add the necessary data/strings to the top of the S3 page. If you can upload the image of the furan compound to the relevant wiki folder I can add it to the wiki (though by looking at the relevant S4 wiki page, you can probably work out how to do this yourself by copying/pasting/modifying the relevant text?

Once it's there, can you add any links to relevant Github issues talking about the synthesis of this compound, again as per the S4 page, so that we have no orphan issues? Once all done we can add in the links to the current Google docs you have that describe the synthetic chemistry synopsis. Once that's all done we can close this Issue.

MFernflower commented 5 years ago

I do wonder if getting a quote from a custom synthesis company would be a good idea @mattodd @mbhebhe

MFernflower commented 5 years ago

@mattodd a small stub of information has been added to the wiki - still waiting on the synthchem google docs writeup

MFernflower commented 5 years ago

@mbhebhe I see you are using triphenylphosphine in your Staudinger Reduction - IIRC @mcoster has had better results using tributyl or triethyl phosphine (maybe meet in the middle and use tri-n-propyl phosphine?)

mbhebhe commented 5 years ago

I will try the triphenylphosphine first and if it doesn't work we will see from then

MFernflower commented 5 years ago

@mbhebhe this might be of use to you https://link.springer.com/article/10.1007%2FBF02974006

MFernflower commented 5 years ago

Closing this - check the S3 wiki DCNYS @mattodd