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OpenSourceMycetoma / Series-2-Aminothiazoles

Series 2
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interesting paper #11

Open MFernflower opened 1 year ago

MFernflower commented 1 year ago

https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c00960

Thoughts @mattodd

mattodd commented 1 year ago

Thanks for pointing this out. It might be worth trying to evaluate some of these, given their similarity of origin. @dosreic this looks like it might be a DNDi-affiliated project - with Ivan Scandale - so I wonder if you might be able to advise on compound availability. If it's not simple, I'm happy to write to the corresponding author, Natalie Hawryluk.

dosreic commented 1 year ago

Hi Matt,

It’s been very difficult to get hold of this compound within DNDi. The legal team has been adamant about the need of an MTA and, at the same time, they have been very busy.

I will keep trying, but I don’t have high hopes, unfortunately.

Best wishes and have a great week, Luiza

Luiza Cruz, PhD I Drug Discovery Coordinator Drugs for Neglected Diseases initiative (DNDi) Rua São José 70 – Sala 601 - Centro | ZIP 20010020 Rio de Janeiro | Brazil M: +55 37 999072470 | @.**@.> dndi.org

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De: Mat Todd @.> Enviada em: sábado, 20 de maio de 2023 09:27 Para: OpenSourceMycetoma/Series-2-Aminothiazoles @.> Cc: Luiza Cruz @.>; Mention @.> Assunto: Re: [OpenSourceMycetoma/Series-2-Aminothiazoles] interesting paper (Issue #11)

Thanks for pointing this out. It might be worth trying to evaluate some of these, given their similarity of origin. @dosreichttps://github.com/dosreic this looks like it might be a DNDi-affiliated project - with Ivan Scandale - so I wonder if you might be able to advise on compound availability. If it's not simple, I'm happy to write to the corresponding author, Natalie Hawryluk.

— Reply to this email directly, view it on GitHubhttps://github.com/OpenSourceMycetoma/Series-2-Aminothiazoles/issues/11#issuecomment-1555901008, or unsubscribehttps://github.com/notifications/unsubscribe-auth/A4KDXHWF3BHVUY4SRVNV3F3XHC2AVANCNFSM6AAAAAAR7MBT2U. You are receiving this because you were mentioned.Message ID: @.***>

mattodd commented 1 year ago

@dosreic is attempting to secure a suitable MTA with @wwjvdsande so that we can source/evaluate these compounds. Can catch up on status of this at the monthly meeting that follows OpenSourceMycetoma/Monthly-zoom-meetings#6