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OpenSourceMycetoma / series-5-benzimidazoles

After screening the pandemic response box, two benzidazoles were able to prolong larval survival in Madurella mycetomatis infected larvae. Furthermore all three also showed some acivity against Falciformispora senegalensis, another prominent mycetoma causative agent.
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DNDI benzimidazole compound #4

Closed MFernflower closed 5 months ago

MFernflower commented 5 months ago

https://dndi.org/research-development/portfolio/oxfendazole/

Any way Wendy's team can get some for testing?

Or has this molecule already been tested?

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MFernflower commented 5 months ago

Closing this at it was tested before and found to not be potent

I still do wonder however if DNDI's other late state drug (Fexinidazole) could be anti fungal however

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