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OstfriesenBI / PredmiRNA

A set of scripts and tools to train a classifier for pre-miRNA Recognition
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Feature calculation: Normalized MFE (dG) #18

Closed Finesim97 closed 5 years ago

Finesim97 commented 5 years ago

R/Python Script Input: csv file with sequence length and the MFE:

"comment","sequencelength","mfe"
"Test123 457Test healp",18,-29.90
"fefefe wefwe ffff", 4,-6.90

The input mfe has to be divided by the length, this is ok for sequence under 40nt above that, there is no linearity applicable (On the Normalization of the Minimum Free Energy of RNAs by Sequence Length). There should a warning or sth like that.

Output: csv file with the normalized MFE: "comment","normalizedmfe" "Test123 457Test healp",-1.6611 "fefefe wefwe ffff",-1.725