PHI-base / curation

PHI-base curation
0 stars 0 forks source link

Can we curate genetic crosses? #134

Open MPiovesana opened 1 year ago

MPiovesana commented 1 year ago

Ticket dedicated to the discussion of the curation of genotypes derived from genetic crosses.

MPiovesana commented 1 year ago

In some papers, a known wt / reference strain is crossed to a clinical / environmental strain of unknown background to introduce natural variation into the wt background. In such cases, the progeny often displays an altered chemical resistance phenotype associated with a point mutation derived from the natural isolate. Can such genotypes be curated in PHI-Canto?

MPiovesana commented 1 year ago

A case example is found in ticket #129 .