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PHI-base curation
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PMID: 20624958 A unique wheat disease resistance-like gene governs effector-triggered susceptibility to necrotrophic pathogens. #59

Open CuzickA opened 4 years ago

ValWood commented 4 years ago

The pathogens that cause the diseases tan spot and Stagonospora nodorum blotch on wheat produce effectors (host-selective toxins) that induce susceptibility in wheat lines harboring corresponding toxin sensitivity genes.

I can't find what the species are, they keep referring to the diseases as the pathogens. I figure that one pathogen is Stagonospora nodorum

but what is the other one?

ValWood commented 4 years ago

We could curate table 1 mutants if it was clear whether these base positions applied to the spliced or unspliced transcript. It might be nice to capture:

Sequence analysis of these six lines indicated that Novo, Puseas, and Huo Mai all had a nonsense mutation at the same position within the LRR domain (Table 1) The lines Siu Mak, Ching Feng, and TA2601 all had frameshift mutations at different positions within the gene. Together, these results in- dicated that the S/TPK-NBS-LRR–like gene was Tsn1 and that all three major domains are essential for Tsn1 function.

Action check with authors ?

ValWood commented 4 years ago

This paper is mainly about 1)Comparative genomics 2) Allelic diversity 3) transcriptional regulation

of tsn1, and these are out of scope for PHi-BAse

ValWood commented 4 years ago

@CuzickA Link to session seems to have disappeared?

CuzickA commented 4 years ago

https://canto.phi-base.org/curs/9b441be20c62bb06

I've not had a chance to look at this one yet.

ValWood commented 4 years ago

Ah right that's OK. I was just looking for examples when I was on the multispecies call last nigh.

CuzickA commented 4 years ago

absence of protein prtoein interaction phenotype to capture @ValWood