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Pathogen-Host Interaction Phenotype Ontology
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oxidative burst vs ROS #132

Closed ValWood closed 5 years ago

ValWood commented 5 years ago

Is the reactive oxygen species (ROS) burst the same or different from

PHIPO:0000927 | pathogen host interaction oxidative burst present in host

I ask because it seems this must be ROS since it has

increased host H202 production resulting from oxidative burst

and H202 is a ROS

If so is ROS more commonly used for describing PTI and should the primary term name be altered?

ValWood commented 5 years ago

curating PMID:30610168

ValWood commented 5 years ago

I think these are the same To investigate whether MoChia1 triggers ROS production in vivo, we examined the ROS levels of the transgenic plants using 3,3-diaminobenzidine (DAB) staining, revealing that more H2O2 accumulated in the DEX:MoChia1 plants following treatment with 30 mM DEX (Figure 1E).

To simplify I would just have

PHIPO:0000927 | pathogen induced ROS production by host
synonym pathogen host interaction oxidative burst present in host synonym host H202 production resulting from oxidative burst synonym increased host H202 production resulting from oxidative burst (i.e merge in)

The pathogen induces ROS production. This seems to be just to demonstrate that the molecule inductes PTI?

Do you think that would seem OK? H202 is just a 'readout', it is a standard ROS used to confirm that ROS is induced.

Or was your previous use to capture anything more?

CuzickA commented 5 years ago

Currently we have image

oxidative burst/respiratory burst GO:0045730 and GO:0002679 leads to the production of ROS

_Is the reactive oxygen species (ROS) burst the same or different from

PHIPO:0000927 | pathogen host interaction oxidative burst present in host_ Yes this is the same

I could rename PHIPO:0000927 as above, add synonyms and obsolete 'increased host H202 production resulting from oxidative burst' as I agree this is a readout of Oxidative/respiratory burst.

'pathogen host interaction oxidative burst absent in host' would also need to be renamed perhaps to

'absence of pathogen induced ROS production by host'

ValWood commented 5 years ago

Sounds good..... We will probably be able to collapse a few things like this where the specificity isn't so important or people are just using slightly different experiments to show the same phenomena.

Did you figure out how to merge term yet?

If not, should do that soon.

CuzickA commented 5 years ago

Made above changes to term name Merged increased host H202 production resulting from oxidative burst PHIPO:0000926 into pathogen induced ROS production by host PHIPO:0000927 2753b45