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PHI-base / phipo

Pathogen-Host Interaction Phenotype Ontology
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Edit term label 'PHIPO:0000992 increased expression of a host defense related marker gene involved in pathogen interaction' #308

Closed CuzickA closed 3 years ago

CuzickA commented 3 years ago

to PHIPO:0000992 increased expression of a host defense related marker gene protein involved in pathogen interaction

This will make it clearer as to whether the the phenotype relates to RNA or Protein

https://github.com/PHI-base/config/issues/51

ans also aligns with PHIPO:0001144 decreased level of host defense related marker gene RNA involved in a pathogen interaction

CuzickA commented 3 years ago

f64715c

ValWood commented 3 years ago

PHIPO:0000992 increased expression of a host defense related marker gene protein involved in pathogen interaction

sounds a bit odd. It seems strange to include. the fact that it is a "marker" in the term name. This isn't really part of the phenotype. Any Gene/protein can be a 'marker' it only means the gene is known to have that behaviour.

also 'marker gene protein' sounds strange.

What would be lost here (biologically) by just saying:

increased expression of a host defence-related ~marker gene~ protein involved in pathogen interaction

and the same for RNA?

CuzickA commented 3 years ago

Yes, I agree. I'll make those edits.

CuzickA commented 3 years ago

Edit PHIPO:0000992 increased expression of a host defense related marker gene protein involved in pathogen interaction to increased expression of a host defense-related protein involved in a pathogen interaction

PHIPO:0001144 decreased level of host defense related marker gene RNA involved in a pathogen interaction to decreased level of host defense-related RNA involved in a pathogen interaction

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