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Pathogen-Host Interaction Phenotype Ontology
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NTR: sensitive to cell wall stress #427

Closed CuzickA closed 5 months ago

CuzickA commented 5 months ago

For https://github.com/PHI-base/curation/issues/196

Preferred term label

sensitive to cell wall stress

Textual definition

A growth phenotype which describes the sensitivity of individuals or populations after exposure to a cell wall stress. Typically, individuals or populations are deemed sensitive to a stress if they grow when exposed to the stress at an intensity at which an individual or population of wild type cell(s) stop growing (and may die).

Suggested parent term

sensitive to stress

CuzickA commented 5 months ago

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Hi @ValWood, I have a question about some overlap we seem to have in the single species branch under 'sensitive to stress' and the 'increased sensitivity to chemical' branch.

My understanding was that the annotations below would be the correct way of describing cell-wall stress expts.

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However, our curator at the time made a direct annotation to 'sensitive to congo red'

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Which annotation do you think is correct and how should we deal with the fact that there are two options to annotate the same thing?

ValWood commented 5 months ago

I would probably use "sensitive to cell wall stress" in this instance. If the purpose of the study is specifically to look at sensitivity to congo red you might want to include it . Or you could make it a descendent of sensitive to cell wall stress (we have done such a similar grouping for DNA damaging agents), or you could record the specific stress chemical as a condition

CuzickA commented 5 months ago

Thanks @ValWood.

So I could place 'sensitive to congo red' as a child of two parents 'sensitive to stress' and the 'increased sensitivity to chemical'

CuzickA commented 5 months ago

NTR: sensitive to cell wall stress 502f9c1

Added 'sensitive to cell wall stress' as an additional parent to 'sensitive to congo red' 5806438

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Looks like this

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