The ML threshold for a reliably methylated cytosine

PacificBiosciences / pb-CpG-tools

Collection of tools for the analysis of CpG data

BSD 3-Clause Clear License

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The ML threshold for a reliably methylated cytosine #70

Open leon945945 opened 6 months ago

leon945945 commented 6 months ago

Hi, as the title described, do you have a recommended ML threshold to judge the cytosine methylation is reliable.

MJoseMo commented 3 months ago

I think it should be bigger than 128 -129. taking into account that when using --pile-up mode count, those with a probability greater than 0.5 are classified as modified.