PBSV to detect heterogeneity?

PacificBiosciences / pbbioconda

PacBio Secondary Analysis Tools on Bioconda. Contains list of PacBio packages available via conda.

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PBSV to detect heterogeneity? #639

Closed TristanJang closed 4 months ago

TristanJang commented 5 months ago

Greetings, I am writing because I am using multiple SV calling tools to detect both consensus and heterogeneity in structural variants in Mycobacterium tuberculosis. Is there a setting or a flag allowing me to change variant allele frequency, allowing me to detect heterogenous structural variants after mapping the reads to its own consensus de novo assembly?

Thanks, Tristan

armintoepfer commented 4 months ago

I don't think so. Pinging @ctsa who is developing the next HiFi SV caller.