The one thing that caught my attention the most is the assumption that there is a single underlying GRN as oppose to somewhat different GSR on different cell types. Could you point me to any references that would justify this assumption? Assuming a single GSR have serious impact on how to analyze scRNAseq data for causal discovery purposes.
Hi, Thanks for developing this useful tool.
The one thing that caught my attention the most is the assumption that there is a single underlying GRN as oppose to somewhat different GSR on different cell types. Could you point me to any references that would justify this assumption? Assuming a single GSR have serious impact on how to analyze scRNAseq data for causal discovery purposes.
thanks FKG