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PengNi / ccsmeth

Detecting DNA methylation from PacBio CCS reads
BSD 3-Clause Clear License
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Where is the master - models #16

Closed hunkui1 closed 2 years ago

hunkui1 commented 2 years ago

Hello, Where is the master - models, can I use model_cpg_attbigru2s_hg002_15kb_s2.b21_epoch7.ckpt?

PengNi commented 2 years ago

Hi @hunkui1 thanks for your interest of ccsmeth. Since ccsmeth v0.2.0, we have changed the pipeline of ccsmeth. So the prior model can't be used with master version of ccsmeth now. I will release a new model ASAP.

Best, Peng

hunkui1 commented 2 years ago

Hello， Hello, is there any difference in the accuracy of methylation between CCSMEth V0.2.0 and CCSMEth V0.1.0？ Thank you!

PengNi commented 2 years ago

We are trying to get a higher accuracy with ccsmeth v0.2.0. But the main difference of the two versions is that, v0.1.0 takes subreads as input, which is very time-consuming, v0.2.0 takes hifi reads as input which is much faster.

hunkui1 commented 2 years ago

This is a good piece of software.In the last few weeks, I have analyzed the genome in combination with the methylation data of V0.1.0 and GFF files. I hope you can make a breakthrough soon. Thank you

hmyh1202 commented 2 years ago

Hi， when to release a new model ?

PengNi commented 2 years ago

model released.