PoonLab / OpenRDP

An open-source re-implementation of the RDP4 recombination detection program
GNU General Public License v3.0
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Random permutation to generate null distribution #84

Open ArtPoon opened 3 months ago

ArtPoon commented 3 months ago

RDP5 provides the option of generating random permutations of the user's input alignment to remove any signal of recombination. Applying recombination tests to the resulting permutations should approximate a null distribution of test statistics, which can be used to assess significance of tests on the original alignment. Note this will scale linearly with the number of permutations requested - on the other hand it should be trivial to parallelize.