PoonLab / vindels

Developing an empirical model of sequence insertion and deletion in virus genomes
1 stars 0 forks source link

02_AG Problem (All Positive Indels) #43

Closed jpalmer37 closed 6 years ago

jpalmer37 commented 6 years ago

The data can be found here 02_AG Check

MSA = .fasta Variable Seqs = .csv (only the cherry sequences are shown) Tree = .tree

Let me know if you need more files.

jpalmer37 commented 6 years ago

Here is the box and whisker plot you requested. cherry_branch_lengths

ArtPoon commented 6 years ago

That's interesting, AG is definitely different compared to some of the other groups. What are the units of branch length?

jpalmer37 commented 6 years ago

Total elapsed time in years. (years sequence 1 + years sequence 2 = total years of cherry pair)

ArtPoon commented 6 years ago

Years is a difficult scale to compare across subtypes because they will vary in degrees of confidence in calibrating the respective molecular clocks. Can you make the same barplot with branch lengths in expected substitutions, i.e., directly from the ML tree reconstructions prior to clock analysis?

jpalmer37 commented 6 years ago

Here's a boxplot of expected substitutions. For the time being, I excluded subtype F1 because it was giving me some trouble with a tip numbering error. Expected Substitutions

jpalmer37 commented 6 years ago

Strangely, subtype F1 appeared to work fine when I plotted the rooted trees here (made via rtt) as opposed to the unrooted trees in my previous comment.

branch_lengths