This is considered a breaking-change as previously set default alignment scoring parameters are removed in favour of default-values determined by the aligner itself.
If you need specific scoring-matrixes for a certain pathogen (i.e. the analysis of RNA viruses often goes better with some adjusted scoring-parameters) then you can set and tune these scorings yourself now
This is considered a breaking-change as previously set default alignment scoring parameters are removed in favour of default-values determined by the aligner itself.
If you need specific scoring-matrixes for a certain pathogen (i.e. the analysis of RNA viruses often goes better with some adjusted scoring-parameters) then you can set and tune these scorings yourself now