RangeShifter / RScore

RangeShifter's core simulation code
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Deleterious allele frequencies conform to Hardy-Weinberg equilibrium #56

Open TheoPannetier opened 3 months ago

TheoPannetier commented 3 months ago

Chromosome inheritance usage

Experiment: Diploid setting, parent population contains a lethal recessive allele at freq p = 0.6 distributed randomly (parent phenotypes are not expressed). Then the proportion of offspring who express the lethal trait should be around p*p = 0.36. Use a large population to reduce stochastic deviations from this proportion.