Closed stevencox closed 5 years ago
An updated version of the CTD service is provisioned at ctdapi.renci.org.
The service now provides chemical to gene data. With this update, the service is expected to fulfill the near term use cases of the Gamma reasoner.
Code for
are here
This request:
GET /CTD_chemicals_DrugBankIDs/{DrugBankIDs}/
produces this response:
[
{
"ChemicalName": "Imatinib Mesylate",
"ChemicalID": "MESH:D000068877",
"CasRN": "",
"Definition": "A tyrosine kinase inhibitor and ANTINEOPLASTIC AGENT that inhibits the BCR-ABL kinase created by chromosome rearrangements in CHRONIC MYELOID LEUKEMIA and ACUTE LYMPHOBLASTIC LEUKEMIA, as well as PDG-derived tyrosine kinases that are overexpressed in gastrointestinal stromal tumors.",
"ParentIDs": "MESH:D001549|MESH:D010879|MESH:D011743",
"TreeNumbers": "D02.065.277.456|D02.241.223.100.100.435|D02.455.426.559.389.127.085.465|D03.383.606.405|D03.383.742.349",
"ParentTreeNumbers": "D02.065.277|D02.241.223.100.100|D02.455.426.559.389.127.085|D03.383.606|D03.383.742",
"Synonyms": "Alpha-(4-methyl-1-piperazinyl)-3'-((4-(3-pyridyl)-2-pyrimidinyl)amino)-p-tolu-p-toluidide|CGP57148|CGP 57148|CGP-57148|CGP57148B|Gleevec|Glivec|Imatinib|Imatinib Methanesulfonate|Mesylate, Imatinib|Methanesulfonate, Imatinib|ST1571|ST 1571|STI571|STI 571|STI-571",
"DrugBankIDs": "DB00619"
}
]
Provision a CTD smartAPI generated via smartBag.
Here's the GitHub repo
Dependent on smartBag
The API endpoint is here