RitchieLabIGH / IRFinder

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IRFinder Diff results p-value #26

Closed rezarahman12 closed 1 year ago

rezarahman12 commented 1 year ago

Dear Claudio, I've run IRFinder Diff. However, the output file has DESeq2.padj.CTR_TTX. My data does not produce any IR event significant after adjustment. So, we need to consider the unadjusted p-value for significance. However, I did not find the p-value column in the outfile. Please advise sorting this out to get the p-value in the output file instead of the adjusted p-value.

I appreciate your help.

Best Reza

CloXD commented 1 year ago

Hello Reza, The method Diff supports multiple groups, performing a pairwise comparison for each combination. In the file all_results_DESeq2.tsv there is a summary of all the comparisons, meanwhile in the subfiles called [contrast_name]_DESeq2.tsv there is the full output of DESeq2, including the column p-value. Cheers, Claudio