recommended inputs for whole exome sequencing data

Roth-Lab / pyclone

Probabilistic model for inferring clonal population structure from deep NGS sequencing.

https://bitbucket.org/aroth85/pyclone/wiki/Home

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recommended inputs for whole exome sequencing data #12

Open JakeConway opened 5 years ago

JakeConway commented 5 years ago

We have whole-exome sequencing data with > 65X coverage for all tumors. Would the default values still be the recommended inputs? More specifically, would you suggest changing density, init_method and num_iters?

Thanks in advance!