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Roth-Lab / pyclone

Probabilistic model for inferring clonal population structure from deep NGS sequencing.
https://bitbucket.org/aroth85/pyclone/wiki/Home
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how to use private somation mutation in pyclone? #19

Open YunjieSong opened 4 years ago

YunjieSong commented 4 years ago

With the default parameter, PyClone can only use shared mutations between samples. How can i use private mutations of each sample in pyclone?

pawelqs commented 3 years ago

Did you solve this?

I wonder if we can add the mutation that is absent in one sample with var_counts = 0 and minor_cn = 0. Would be great to get the clarification for this. @aroth85 ?