RussBainer / gCrisprTools

An R/Bioconductor package for the integrated analysis of pooled high-throughput CRISPR/Cas9 or shRNA screening experiments.
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Enable alt ann #17

Closed RussBainer closed 3 years ago

RussBainer commented 3 years ago

Adding functionality for processing libraries with multiply-annotated guides (e.g., CRISPRi and CRISPRa). Practically, this involves adding a set of functions for expanding a provided annotation file and/or fit object on the basis of an "alternative annotation" vector (see man pages).

A key consequence of this is that the code is moving away from using the row.names() attribute in favor of the ID column of the annotation file.