Error in plot.window(...) : need finite 'xlim' values in `SingleCellSignalR::intra_network` and classification about the scores of gene-related pathways

[denvercal1234GitHub]

Hi there,

Thanks for the tool. I have 2 questions.

1. When I was running SingleCellSignalR::intra_network as below, I encountered an error of plot.window(...) : need finite 'xlim' values. How might I fix it within SingleCellSignalR::intra_network?

2. For the gene that was plotted successfully, would you mind clarifying what does the colors (red and pale blue), shapes (circle and square), and especially the scores (0 to...) of the `gene-related pathways" indicate? Are these pathways shown specific to my data in this cluster or just generically by all literatures for this gene ?

3. And, for some genes, that is a network connecting the gene of interest, but no related pathway plots shown. Does this mean there is no known related pathway for this gene in this cluster (even though there might be related pathways)?

Thank you for your help.

SingleCellSignalR::intra_network(data = Seurat_data, goi = rownames(Seurat_data)[15:20], coi = "25", signal = Seurat_SingleCellSignalRsignal, genes=rownames(Seurat_data), cluster=Seurat_1p2clusters26, write=F, c.names=unique(Seurat_1p2clusters26))