about data.tl.spatial_hotspot

[Biomamba]

Dear authors: Thank your for your contribution to stereopy. There is a question really confuse me. Why parameters both use_highly_genes and use_raw can be True in function data.tl.spatial_hotspot()?

[tanliwei-coder]

Sometimes, before spatial_hotspot, we may do some preprocessing which will change the values of expression matrix like normalize_total or log1p, setting use_raw to true represents using the expression matrix in which the values are raw values and setting use_highly_genes to true represents using the subset which only contains the highly variable genes, if both are set to true, the values of expression matrix in the subset are raw values.

[Biomamba]

Sometimes, before spatial_hotspot, we may do some preprocessing which will change the values of expression matrix like normalize_total or log1p, setting use_raw to true represents using the expression matrix in which the values are raw values and setting use_highly_genes to true represents using the subset which only contains the highly variable genes, if both are set to true, the values of expression matrix in the subset are raw values.

Got it， thank you for your reply.