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SWISS-MODEL / covid-19-Annotations-on-Structures

Mapping sequence data onto structures for the Covid-19 Biohackathon April 2020
https://github.com/virtual-biohackathons/covid-19-bh20/wiki/Annotations-on-Structures
MIT License
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Sequence Diff Annotations #23

Closed schdaude closed 4 years ago

schdaude commented 4 years ago

The idea is to visualize diffs between closely related sequences e.g. SARS-CoV vs. SARS-CoV 2. Input are two uniprot ACs. In a first step, the underlying sequences are aligned using Needleman-Wunsch. Annotations arise from non-conserved amino acids. This only makes sense for sequences with high sequence identity.

schdaude commented 4 years ago

Initial version with minimal external dependencies is available.