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Sage-Bionetworks / NF_LandscapePaper_2019

This repository hosts all the code used to generate analyses and figures for the landscape paper
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ks test/gsea for enrichment of drugs in lvs #41

Closed allaway closed 4 years ago

allaway commented 4 years ago

To assess relative "druggability" across LV loading we can apply a k-s test/GSEA to the loading matrix and all druggable targets

allaway commented 4 years ago

@sgosline suggested trying this both across individual drugs (this is likely to result in enrichment of highly polypharmacologic drugs, I'm guessing, and not much else) and then across all drugs combined to find reasonable combinations for individual lvs.