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ProgressReportNumber in the Milestone Tracker is not showing all milestones in some studies. #177

Closed jaybee84 closed 2 years ago

jaybee84 commented 2 years ago

Describe the bug ProgressReportNumber in the Milestone Tracker is not showing milestones 3 and above for some studies.

To Reproduce Steps to reproduce the behavior:

  1. Go to projectLive-NF
  2. Click on NTAP
  3. Go to "Participating Studies"
  4. Type Ray Mattingly in search box and select the "active" study
  5. Scroll down to Milestone Tracker
  6. The dropdown list only shows 2 milestones, but the study has new files with "ProgressReportNumber" as 3 or 4 (https://www.synapse.org/#!Synapse:syn26611101)

Expected behavior All possible milestones (gathered from "ProgressReportNumber" annotation) should be reflected in the dropdown menu as well as the left hand side table in the section Sage Internal milestone or progress report tracking

Screenshots

Screen Shot 2022-03-31 at 1 46 40 PM

Desktop (please complete the following information):

andrewelamb commented 2 years ago

I'm not seeing those milestones for the study "Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas":

 52 <chr [1]>  2020-10-31                        1                     12 NTAP          syn11374357  geneExpression                             Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 53 <chr [1]>  2020-10-31                        1                      1 NTAP          syn11374357  protocol                                   Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 54 <chr [1]>  2020-10-31                        1                     NA NTAP          syn11374357  image                                      Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 55 <chr [1]>  2020-10-31                        1                     NA NTAP          syn11374357  image                                      Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 56 <chr [1]>  2021-04-30                        2                     12 NTAP          syn11374357  geneExpression                             Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 57 <chr [1]>  2021-04-30                        2                     16 NTAP          syn11374357  image                                      Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 58 <chr [1]>  2021-04-30                        2                     NA NTAP          syn11374357  image                                      Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 59 <chr [1]>  2021-04-30                        2                     16 NTAP          syn11374357  image                                      Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas    
# A tibble: 327 × 8
    fileFormat date_uploadestimate reportMilestone estimatedMinNumSamples fundingAgency projectSynID dataType                                   studyName                                                                                                                            
    <list>     <date>                        <int>                  <int> <chr>         <chr>        <chr>                                      <chr>                                                                                                                                
  1 <chr [1]>  NA                               NA                     NA CTF           syn22268689  immunoassay                                Identification and functional characterization of the substrates of LZTR1 (schwannomatosis)                                          
  2 <chr [1]>  NA                               NA                     NA CTF           syn22268689  image                                      Identification and functional characterization of the substrates of LZTR1 (schwannomatosis)                                          
  3 <chr [1]>  NA                               NA                     NA CTF           syn22268689  cell viability                             Identification and functional characterization of the substrates of LZTR1 (schwannomatosis)                                          
  4 <chr [1]>  NA                               NA                     NA CTF           syn22268689  proteomics                                 Identification and functional characterization of the substrates of LZTR1 (schwannomatosis)                                          
  5 <chr [1]>  2020-12-20                       NA                     54 CTF           syn22268639  immunoflourescence                         Understanding the role of purinerigic signaling on tumor formation in a mouse model of Neurofibromatosis Type 1                      
  6 <chr [1]>  2020-12-20                       NA                     12 CTF           syn22268639  immunoassay                                Understanding the role of purinerigic signaling on tumor formation in a mouse model of Neurofibromatosis Type 1                      
  7 <chr [1]>  2021-06-20                       NA                     12 CTF           syn22268639  immunoassay                                Understanding the role of purinerigic signaling on tumor formation in a mouse model of Neurofibromatosis Type 1                      
  8 <chr [1]>  2021-06-20                       NA                     15 CTF           syn22268639  immunoflourescence                         Understanding the role of purinerigic signaling on tumor formation in a mouse model of Neurofibromatosis Type 1                      
  9 <chr [1]>  2020-12-31                       NA                     50 CTF           syn22267284  proteomics                                 Mapping and Identifying the Roles of Protein Glycosylation in Neurofibromatosis 1                                                    
 10 <chr [1]>  2021-06-30                       NA                    100 CTF           syn22267284  immunoassay                                Mapping and Identifying the Roles of Protein Glycosylation in Neurofibromatosis 1                                                    
 11 <chr [1]>  2021-01-01                       NA                    100 CTF           syn22267284  mass spectrometry                          Mapping and Identifying the Roles of Protein Glycosylation in Neurofibromatosis 1                                                    
 12 <chr [1]>  2021-01-01                       NA                    100 CTF           syn22267284  image                                      Mapping and Identifying the Roles of Protein Glycosylation in Neurofibromatosis 1                                                    
 13 <chr [1]>  2021-06-30                       NA                     10 CTF           syn22267284  geneExpression                             Mapping and Identifying the Roles of Protein Glycosylation in Neurofibromatosis 1                                                    
 14 <chr [1]>  2020-12-31                       NA                    100 CTF           syn22267284  enzyme kinetics                            Mapping and Identifying the Roles of Protein Glycosylation in Neurofibromatosis 1                                                    
 15 <chr [1]>  2021-05-01                       NA                     50 CTF           syn22267330  kinetic calcium flux                       Malignant Peripheral Nerve Sheath Tumors Achilles Heel: Combinatorial Targeting of ERBB3 and Calcium Signaling                       
 16 <chr [1]>  2020-12-01                       NA                     25 CTF           syn22267330  immunoassay                                Malignant Peripheral Nerve Sheath Tumors Achilles Heel: Combinatorial Targeting of ERBB3 and Calcium Signaling                       
 17 <chr [1]>  2021-03-01                       NA                     50 CTF           syn22267330  cell viability                             Malignant Peripheral Nerve Sheath Tumors Achilles Heel: Combinatorial Targeting of ERBB3 and Calcium Signaling                       
 18 <chr [1]>  2021-12-01                       NA                     50 CTF           syn22267330  cell viability                             Malignant Peripheral Nerve Sheath Tumors Achilles Heel: Combinatorial Targeting of ERBB3 and Calcium Signaling                       
 19 <chr [1]>  2020-12-01                       NA                     35 CTF           syn22267330  image                                      Malignant Peripheral Nerve Sheath Tumors Achilles Heel: Combinatorial Targeting of ERBB3 and Calcium Signaling                       
 20 <chr [1]>  2021-03-01                       NA                     50 CTF           syn22267330  image                                      Malignant Peripheral Nerve Sheath Tumors Achilles Heel: Combinatorial Targeting of ERBB3 and Calcium Signaling                       
 21 <chr [1]>  2020-12-01                       NA                     80 CTF           syn22268652  immunoassay                                The use of novel YAP/TEAD Hippo pathway inhibitors to target Merlin (NF2) null tumors                                                
 22 <chr [1]>  2021-07-01                       NA                     80 CTF           syn22268652  immunoassay                                The use of novel YAP/TEAD Hippo pathway inhibitors to target Merlin (NF2) null tumors                                                
 23 <chr [1]>  2021-02-01                       NA                    160 CTF           syn22268652  proliferation                              The use of novel YAP/TEAD Hippo pathway inhibitors to target Merlin (NF2) null tumors                                                
 24 <chr [1]>  2022-03-01                       NA                     40 CTF           syn22268652  weight                                     The use of novel YAP/TEAD Hippo pathway inhibitors to target Merlin (NF2) null tumors                                                
 25 <chr [1]>  2020-12-01                       NA                    144 CTF           syn22266606  proteomics                                 Unveiling the molecular mechanisms of neurofibromin regulation for therapeutic targeting in neurofibromatosis type 1                 
 26 <chr [1]>  2022-06-30                       NA                   2000 CTF           syn22266606  immunoassay                                Unveiling the molecular mechanisms of neurofibromin regulation for therapeutic targeting in neurofibromatosis type 1                 
 27 <chr [1]>  2022-06-30                       NA                    100 CTF           syn22266606  weight                                     Unveiling the molecular mechanisms of neurofibromin regulation for therapeutic targeting in neurofibromatosis type 1                 
 28 <chr [1]>  NA                               NA                     24 CTF           syn22267323  metabolomics                               Impact of PRC2 loss on Glutamine metabolism in MPNSTs                                                                                
 29 <chr [2]>  2020-07-31                        1                      1 NTAP          syn11374345  genomicVariant                             Leveraging human induced pluripotent stem cells (iPSCs) to determine the impact of patient-derived NF1 gene mutations on peripheral …
 30 <chr [1]>  2020-07-31                        1                      5 NTAP          syn11374345  immunoassay                                Leveraging human induced pluripotent stem cells (iPSCs) to determine the impact of patient-derived NF1 gene mutations on peripheral …
 31 <chr [1]>  2021-01-31                        2                     NA NTAP          syn11374345  immunoassay                                Leveraging human induced pluripotent stem cells (iPSCs) to determine the impact of patient-derived NF1 gene mutations on peripheral …
 32 <chr [1]>  2021-01-31                        2                      3 NTAP          syn11374345  report                                     Leveraging human induced pluripotent stem cells (iPSCs) to determine the impact of patient-derived NF1 gene mutations on peripheral …
 33 <chr [2]>  2020-02-29                        1                     NA NTAP          syn11374341  geneExpression                             Microenvironmental targets of cutaneous neurofibromas: T-cells and mast cells as tumor contributors                                  
 34 <chr [2]>  2020-02-29                        1                     20 NTAP          syn11374341  image                                      Microenvironmental targets of cutaneous neurofibromas: T-cells and mast cells as tumor contributors                                  
 35 <chr [1]>  2020-02-29                        1                      1 NTAP          syn11374341  protocol                                   Microenvironmental targets of cutaneous neurofibromas: T-cells and mast cells as tumor contributors                                  
 36 <chr [1]>  2020-08-31                        2                     20 NTAP          syn11374341  proteomics                                 Microenvironmental targets of cutaneous neurofibromas: T-cells and mast cells as tumor contributors                                  
 37 <chr [1]>  2021-02-28                        3                     20 NTAP          syn11374341  proteomics                                 Microenvironmental targets of cutaneous neurofibromas: T-cells and mast cells as tumor contributors                                  
 38 <chr [1]>  2020-02-29                        1                     NA NTAP          syn4939918   geneExpression                             Perpetuating NF1 heterozygous and NF1 homozygous negative plexiform neurofibroma-derived tumor cells through the generation of induc…
 39 <chr [3]>  2020-02-29                        1                     NA NTAP          syn4939918   gene expression, genomic variants          Perpetuating NF1 heterozygous and NF1 homozygous negative plexiform neurofibroma-derived tumor cells through the generation of induc…
 40 <chr [1]>  2020-02-29                        1                     NA NTAP          syn4939918   NA                                         Perpetuating NF1 heterozygous and NF1 homozygous negative plexiform neurofibroma-derived tumor cells through the generation of induc…
 41 <chr [1]>  2020-02-29                        1                     NA NTAP          syn4939918   image                                      Perpetuating NF1 heterozygous and NF1 homozygous negative plexiform neurofibroma-derived tumor cells through the generation of induc…
 42 <chr [1]>  2021-02-28                        2                     NA NTAP          syn4939918   image                                      Perpetuating NF1 heterozygous and NF1 homozygous negative plexiform neurofibroma-derived tumor cells through the generation of induc…
 43 <chr [1]>  2021-02-28                        2                     NA NTAP          syn4939918   NA                                         Perpetuating NF1 heterozygous and NF1 homozygous negative plexiform neurofibroma-derived tumor cells through the generation of induc…
 44 <chr [1]>  2021-02-28                        2                     NA NTAP          syn4939918   NA                                         Perpetuating NF1 heterozygous and NF1 homozygous negative plexiform neurofibroma-derived tumor cells through the generation of induc…
 45 <chr [1]>  2021-02-28                        2                     NA NTAP          syn4939918   ImmunoAssay                                Perpetuating NF1 heterozygous and NF1 homozygous negative plexiform neurofibroma-derived tumor cells through the generation of induc…
 46 <chr [1]>  NA                               NA                     NA NTAP          syn4939918   NA                                         Perpetuating NF1 heterozygous and NF1 homozygous negative plexiform neurofibroma-derived tumor cells through the generation of induc…
 47 <chr [1]>  2020-01-31                        1                     NA NTAP          syn11374333  image                                      Cutaneous Neurofibroma - Models, Biology, and Translation                                                                            
 48 <chr [1]>  2020-01-31                        1                     NA NTAP          syn11374333  image                                      Cutaneous Neurofibroma - Models, Biology, and Translation                                                                            
 49 <chr [1]>  2021-01-31                        2                     NA NTAP          syn11374333  image                                      Cutaneous Neurofibroma - Models, Biology, and Translation                                                                            
 50 <chr [1]>  2021-01-31                        2                     NA NTAP          syn11374333  Drug sensitivity                           Cutaneous Neurofibroma - Models, Biology, and Translation                                                                            
 51 <chr [1]>  2021-01-31                        2                     NA NTAP          syn11374333  Results                                    Cutaneous Neurofibroma - Models, Biology, and Translation                                                                            
 52 <chr [1]>  2020-10-31                        1                     12 NTAP          syn11374357  geneExpression                             Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 53 <chr [1]>  2020-10-31                        1                      1 NTAP          syn11374357  protocol                                   Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 54 <chr [1]>  2020-10-31                        1                     NA NTAP          syn11374357  image                                      Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 55 <chr [1]>  2020-10-31                        1                     NA NTAP          syn11374357  image                                      Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 56 <chr [1]>  2021-04-30                        2                     12 NTAP          syn11374357  geneExpression                             Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 57 <chr [1]>  2021-04-30                        2                     16 NTAP          syn11374357  image                                      Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 58 <chr [1]>  2021-04-30                        2                     NA NTAP          syn11374357  image                                      Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 59 <chr [1]>  2021-04-30                        2                     16 NTAP          syn11374357  image                                      Deconstruction and Reconstitution of NF1 Cutaneous Neurofibromas                                                                     
 60 <chr [1]>  2020-03-21                        1                     NA NTAP          syn11374337  protocol                                   Use of the mouse model of cutaneous neurofibromas for identification of cells of origin and drug screening studies                   
 61 <chr [2]>  2020-03-21                        4                      2 NTAP          syn11374337  geneExpression                             Use of the mouse model of cutaneous neurofibromas for identification of cells of origin and drug screening studies                   
 62 <chr [1]>  2020-03-21                        1                     NA NTAP          syn11374337  image                                      Use of the mouse model of cutaneous neurofibromas for identification of cells of origin and drug screening studies                   
 63 <chr [1]>  2020-12-30                        2                     NA NTAP          syn11374337  geneExpression                             Use of the mouse model of cutaneous neurofibromas for identification of cells of origin and drug screening studies                   
 64 <chr [1]>  2020-12-30                        2                     NA NTAP          syn11374337  image                                      Use of the mouse model of cutaneous neurofibromas for identification of cells of origin and drug screening studies                   
 65 <chr [2]>  2020-12-30                        2                      2 NTAP          syn11374337  geneExpression                             Use of the mouse model of cutaneous neurofibromas for identification of cells of origin and drug screening studies                   
 66 <chr [1]>  2021-05-01                       NA                     20 CTF           syn23532273  image                                      Exploiting macropinocytosis for therapeutic delivery to Nf2-deficient schwannoma cells                                               
 67 <chr [1]>  2021-05-01                       NA                     60 CTF           syn23532273  image                                      Exploiting macropinocytosis for therapeutic delivery to Nf2-deficient schwannoma cells                                               
 68 <chr [1]>  2021-10-31                       NA                    300 CTF           syn23532273  image                                      Exploiting macropinocytosis for therapeutic delivery to Nf2-deficient schwannoma cells                                               
 69 <chr [1]>  2021-10-31                       NA                    300 CTF           syn23532273  image                                      Exploiting macropinocytosis for therapeutic delivery to Nf2-deficient schwannoma cells                                               
 70 <chr [2]>  2021-03-01                       NA                     64 CTF           syn23532255  Pharmacokinetic data                       TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 71 <chr [2]>  2021-05-01                       NA                    250 CTF           syn23532255  Clinical score and survival rate           TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 72 <chr [2]>  2021-07-01                       NA                    960 CTF           syn23532255  Clinical score and survival rate           TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 73 <chr [2]>  2021-11-30                       NA                    560 CTF           syn23532255  Tumor volume                               TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 74 <chr [2]>  2021-11-30                       NA                     46 CTF           syn23532255  Tumor volume and number of tumor masses    TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 75 <chr [2]>  2021-11-30                       NA                     36 CTF           syn23532255  Qualitative protein expression             TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 76 <chr [2]>  2021-11-30                       NA                     36 CTF           syn23532255  Metabolites concentration in tumor samples TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 77 <chr [2]>  2021-11-30                       NA                     18 CTF           syn23532255  Protein expression                         TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 78 <chr [2]>  2021-11-30                       NA                     18 CTF           syn23532255  Enzymatic activity                         TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 79 <chr [1]>  2021-11-30                       NA                     10 CTF           syn23532255  Docking of TRAP1 inhibitors                TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 80 <chr [2]>  2021-11-30                       NA                     30 CTF           syn23532255  TRAP1 activity                             TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 81 <chr [2]>  2021-11-30                       NA                     20 CTF           syn23532255  Hsp90 activity                             TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 82 <chr [2]>  2021-11-30                       NA                     40 CTF           syn23532255  Enzymatic activity                         TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 83 <chr [2]>  2021-11-30                       NA                     20 CTF           syn23532255  Cell viability                             TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 84 <chr [2]>  2021-11-30                       NA                     20 CTF           syn23532255  Cell proliferation                         TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 85 <chr [2]>  2021-11-30                       NA                     20 CTF           syn23532255  In vitro tumor growth                      TRAPping neurofibromas. Inhibition of the mitochondrial chaperone TRAP1 as an anti-neoplastic strategy for NF1-associated tumors     
 86 <chr [2]>  2021-10-15                       NA                      1 CTF           syn23532271  immunoassay                                Experimental Therapeutic Evaluation of PSC5-6 using a pre-clinical Mouse Model of Neurofibromatosis Type 1                           
 87 <chr [2]>  2021-10-15                       NA                     20 CTF           syn23532271  image                                      Experimental Therapeutic Evaluation of PSC5-6 using a pre-clinical Mouse Model of Neurofibromatosis Type 1                           
 88 <chr [2]>  2021-10-15                       NA                     24 CTF           syn23532271  weight                                     Experimental Therapeutic Evaluation of PSC5-6 using a pre-clinical Mouse Model of Neurofibromatosis Type 1                           
 89 <chr [2]>  2021-10-15                       NA                     18 CTF           syn23532271  pharmacokinetic study                      Experimental Therapeutic Evaluation of PSC5-6 using a pre-clinical Mouse Model of Neurofibromatosis Type 1                           
 90 <chr [1]>  2023-01-01                        2                   1000 NTAP          syn23664726  genomicVariant                             Evaluating genetic modifiers of cutaneous neurofibromas in adults with Neurofibromatosis Type 1                                      
 91 <chr [1]>  2021-06-30                        1                      2 NTAP          syn23662493  geneExpression                             Developing ELISA/IHC-Capable NF1 Monooclonal Antibody                                                                                
 92 <chr [1]>  2021-06-30                        1                      1 NTAP          syn23662493  proteomics                                 Developing ELISA/IHC-Capable NF1 Monooclonal Antibody                                                                                
 93 <chr [1]>  2021-06-30                        1                      5 NTAP          syn23662493  immunoassay                                Developing ELISA/IHC-Capable NF1 Monooclonal Antibody                                                                                
 94 <chr [1]>  2021-06-30                        1                     40 NTAP          syn23662493  immunoassay                                Developing ELISA/IHC-Capable NF1 Monooclonal Antibody                                                                                
 95 <chr [1]>  2021-06-30                        1                     49 NTAP          syn23662493  image                                      Developing ELISA/IHC-Capable NF1 Monooclonal Antibody                                                                                
 96 <chr [1]>  2020-12-18                       NA                    109 other         syn23651229  mutational data, copy number alterations   Ultra-low-pass whole genome sequencing of plasma cfDNA from patients with plexiform neurofibroma and malignant peripheral nerve shea…
 97 <chr [2]>  2021-02-01                       NA                    105 CDMRP         syn23639889  Immunoassay                                TYK2 as a Biomarker and Therapeutic Target for NF1-Associated Malignant Peripheral Nerve Sheath Tumors                               
 98 <chr [4]>  2021-03-15                       NA                     18 CDMRP         syn23639889  cell viability                             TYK2 as a Biomarker and Therapeutic Target for NF1-Associated Malignant Peripheral Nerve Sheath Tumors                               
 99 <chr [1]>  2021-01-01                       NA                      6 CDMRP         syn23639889  geneExpression                             TYK2 as a Biomarker and Therapeutic Target for NF1-Associated Malignant Peripheral Nerve Sheath Tumors                               
100 <chr [4]>  2021-03-15                       NA                      6 CDMRP         syn23639889  immunoassay                                TYK2 as a Biomarker and Therapeutic Target for NF1-Associated Malignant Peripheral Nerve Sheath Tumors                               
101 <chr [2]>  2021-03-15                       NA                      3 CDMRP         syn23639889  geneExpression                             TYK2 as a Biomarker and Therapeutic Target for NF1-Associated Malignant Peripheral Nerve Sheath Tumors                               
102 <chr [2]>  2022-01-15                       NA                     16 CDMRP         syn23639889  weight                                     TYK2 as a Biomarker and Therapeutic Target for NF1-Associated Malignant Peripheral Nerve Sheath Tumors                               
103 <chr [4]>  2022-06-15                       NA                     16 CDMRP         syn23639889  image                                      TYK2 as a Biomarker and Therapeutic Target for NF1-Associated Malignant Peripheral Nerve Sheath Tumors                               
104 <chr [1]>  2020-08-15                       NA                     96 GFF           syn21650326  image                                      Neuroprotection and optic nerve regeneration in a mouse NF1 OPG model                                                                
105 <chr [1]>  2020-05-15                       NA                     35 GFF           syn21650326  image                                      Neuroprotection and optic nerve regeneration in a mouse NF1 OPG model                                                                
106 <chr [1]>  2020-05-10                       NA                    192 GFF           syn21650326  image                                      Neuroprotection and optic nerve regeneration in a mouse NF1 OPG model                                                                
107 <chr [1]>  2020-05-10                       NA                     40 GFF           syn21650326  image                                      Neuroprotection and optic nerve regeneration in a mouse NF1 OPG model                                                                
108 <chr [1]>  2020-05-10                       NA                      4 GFF           syn21650326  geneExpression                             Neuroprotection and optic nerve regeneration in a mouse NF1 OPG model                                                                
109 <chr [1]>  2020-12-31                       NA                      4 GFF           syn21650395  NA                                         Optimizing strategies to improve visual recovery from NF1 optic glioma                                                               
110 <chr [1]>  2021-03-31                       NA                      4 GFF           syn21650395  NA                                         Optimizing strategies to improve visual recovery from NF1 optic glioma                                                               
111 <chr [1]>  2021-12-31                       NA                      4 GFF           syn21650395  NA                                         Optimizing strategies to improve visual recovery from NF1 optic glioma                                                               
112 <chr [1]>  2021-12-31                       NA                      4 GFF           syn21650395  NA                                         Optimizing strategies to improve visual recovery from NF1 optic glioma                                                               
113 <chr [1]>  2021-06-30                       NA                      4 GFF           syn21650395  NA                                         Optimizing strategies to improve visual recovery from NF1 optic glioma                                                               
114 <chr [1]>  2021-12-31                       NA                      4 GFF           syn21650395  NA                                         Optimizing strategies to improve visual recovery from NF1 optic glioma                                                               
115 <chr [1]>  2021-03-31                       NA                      4 GFF           syn21650395  NA                                         Optimizing strategies to improve visual recovery from NF1 optic glioma                                                               
116 <chr [1]>  2022-03-31                       NA                      4 GFF           syn21650395  NA                                         Optimizing strategies to improve visual recovery from NF1 optic glioma                                                               
117 <chr [1]>  2020-12-30                       NA                      3 GFF           syn21650404  geneExpression                             New strategies of protecting RGCs and promoting optic nerve regeneration                                                             
118 <chr [1]>  2020-12-30                       NA                     12 GFF           syn21650404  geneExpression                             New strategies of protecting RGCs and promoting optic nerve regeneration                                                             
119 <chr [1]>  2020-09-15                       NA                    100 GFF           syn21650464  image                                      Structural and functional restoration of the visual system in NF1                                                                    
120 <chr [1]>  2020-09-15                       NA                     50 GFF           syn21650464  image                                      Structural and functional restoration of the visual system in NF1                                                                    
121 <chr [1]>  2020-09-15                       NA                    200 GFF           syn21650464  image                                      Structural and functional restoration of the visual system in NF1                                                                    
122 <chr [1]>  2020-12-15                       NA                    200 GFF           syn21650464  image                                      Structural and functional restoration of the visual system in NF1                                                                    
123 <chr [1]>  2020-12-15                       NA                      4 GFF           syn21650464  geneExpression                             Structural and functional restoration of the visual system in NF1                                                                    
124 <chr [1]>  NA                               NA                     NA GFF           syn21650476  geneExpression                             Generation and neuroprotective studies of NF1 patient-derived RGCs                                                                   
125 <chr [1]>  NA                               NA                     NA GFF           syn21650476  geneExpression                             Generation and neuroprotective studies of NF1 patient-derived RGCs                                                                   
126 <chr [1]>  NA                               NA                     NA GFF           syn21650476  image                                      Generation and neuroprotective studies of NF1 patient-derived RGCs                                                                   
127 <chr [1]>  NA                               NA                     NA GFF           syn21650476  image                                      Generation and neuroprotective studies of NF1 patient-derived RGCs                                                                   
128 <chr [1]>  2020-10-01                       NA                      5 GFF           syn21650484  geneExpression                             Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
129 <chr [1]>  2021-10-01                       NA                      5 GFF           syn21650484  geneExpression                             Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
130 <chr [1]>  2022-01-31                       NA                      5 GFF           syn21650484  geneExpression                             Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
131 <chr [1]>  2020-10-01                       NA                     50 GFF           syn21650484  image                                      Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
132 <chr [1]>  2021-10-01                       NA                     50 GFF           syn21650484  image                                      Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
133 <chr [1]>  2022-01-31                       NA                     50 GFF           syn21650488  geneExpression                             Human stem cell-derived RGCs for optic nerve regeneration                                                                            
134 <chr [1]>  NA                               NA                     NA GFF           syn21650488  geneExpression                             Human stem cell-derived RGCs for optic nerve regeneration                                                                            
135 <chr [1]>  NA                               NA                     NA GFF           syn21650488  image                                      Human stem cell-derived RGCs for optic nerve regeneration                                                                            
136 <chr [1]>  NA                               NA                     NA GFF           syn21650488  image                                      Human stem cell-derived RGCs for optic nerve regeneration                                                                            
137 <chr [1]>  NA                               NA                      5 GFF           syn21650488  chromosomal karyotypes                     Human stem cell-derived RGCs for optic nerve regeneration                                                                            
138 <chr [1]>  NA                               NA                     NA GFF           syn21650493  geneExpression                             Retina regeneration in zebrafish-Endogenous RGC replacement                                                                          
139 <chr [1]>  NA                               NA                     NA GFF           syn21650493  chromatinActivity                          Retina regeneration in zebrafish-Endogenous RGC replacement                                                                          
140 <chr [1]>  NA                               NA                     NA GFF           syn21650493  drugScreen                                 Retina regeneration in zebrafish-Endogenous RGC replacement                                                                          
141 <chr [1]>  2021-06-30                       NA                     10 GFF           syn21650499  geneExpression                             Factors that promote ganglion cell regeneration                                                                                      
142 <chr [2]>  NA                               NA                     60 GFF           syn21650480  image                                      RGC differentiation and transplantation for NF1 OPG                                                                                  
143 <chr [2]>  NA                               NA                     60 GFF           syn21650366  image                                      Axon regeneration and vision restoration in NF1 OPG                                                                                  
144 <chr [1]>  2020-09-30                       NA                     30 GFF           syn21650484  Materials biodegradation                   Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
145 <chr [3]>  NA                               NA                     20 GFF           syn21650480  geneExpression                             RGC differentiation and transplantation for NF1 OPG                                                                                  
146 <chr [2]>  NA                               NA                     60 GFF           syn21650480  image                                      RGC differentiation and transplantation for NF1 OPG                                                                                  
147 <chr [2]>  NA                               NA                     60 GFF           syn21650366  image                                      Axon regeneration and vision restoration in NF1 OPG                                                                                  
148 <chr [2]>  NA                               NA                     20 GFF           syn21650366  image                                      Axon regeneration and vision restoration in NF1 OPG                                                                                  
149 <chr [1]>  NA                               NA                     NA NA            NA           NA                                         NA                                                                                                                                   
150 <chr [1]>  2020-09-30                       NA                     23 GFF           syn21650484  Materials shear modulus, time to stability Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
151 <chr [1]>  2020-09-30                       NA                      8 GFF           syn21650484  Materials Young modulus                    Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
152 <chr [1]>  2020-09-30                       NA                      3 GFF           syn21650484  Materials gel point imaging                Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
153 <chr [1]>  2020-09-30                       NA                     30 GFF           syn21650484  Materials gel point analysis               Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
154 <chr [1]>  2020-09-30                       NA                      2 GFF           syn21650484  Materials transition temperatures          Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
155 <chr [1]>  2020-09-30                       NA                      2 GFF           syn21650484  Materials molecular weights                Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
156 <chr [1]>  2020-09-30                       NA                      6 GFF           syn21650484  Materials chemical structure               Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
157 <chr [1]>  2020-09-30                       NA                     50 GFF           syn21650484  image                                      Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
158 <chr [1]>  2020-09-30                       NA                      1 GFF           syn21650484  image                                      Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
159 <chr [1]>  2020-09-30                       NA                     30 GFF           syn21650484  Intensity distribution                     Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
160 <chr [1]>  2020-09-30                       NA                      8 GFF           syn21650484  Cell marker expression                     Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
161 <chr [1]>  2020-09-30                       NA                      8 GFF           syn21650484  Cell marker expression                     Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
162 <chr [1]>  2020-09-30                       NA                     30 GFF           syn21650484  H&E staining of retinas                    Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
163 <chr [1]>  2020-09-30                       NA                    108 GFF           syn21650484  Back of the eye and retina imaging         Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
164 <chr [1]>  2020-09-30                       NA                      1 GFF           syn21650484  Gel presence and in vivo degradation       Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
165 <chr [1]>  2020-09-30                       NA                    250 GFF           syn21650484  In vivo cell engraftment                   Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
166 <chr [1]>  2020-09-30                       NA                      1 GFF           syn21650484  In vivo engraftment analysis               Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
167 <chr [1]>  2020-09-30                       NA                     12 GFF           syn21650484  In vivo immune response                    Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
168 <chr [1]>  2020-09-30                       NA                     12 GFF           syn21650484  In vivo muller cell                        Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
169 <chr [1]>  2021-09-30                       NA                     10 GFF           syn21650484  IPSC marker expression                     Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
170 <chr [1]>  2021-09-30                       NA                      5 GFF           syn21650484  IPSC gene expression                       Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
171 <chr [1]>  2021-09-30                       NA                     10 GFF           syn21650484  IPSC pluripotency                          Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
172 <chr [1]>  2021-09-30                       NA                     30 GFF           syn21650484  RGC marker characterization                Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
173 <chr [1]>  2021-09-30                       NA                     10 GFF           syn21650484  RGC marker characterization                Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
174 <chr [1]>  2021-09-30                       NA                      5 GFF           syn21650484  RGC gene expression                        Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
175 <chr [1]>  2021-09-30                       NA                      5 GFF           syn21650484  electrophysiology                          Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
176 <chr [1]>  2021-09-30                       NA                     10 GFF           syn21650484  RGC sorting                                Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
177 <chr [1]>  2021-09-30                       NA                     50 GFF           syn21650484  In vitro viability imaging                 Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
178 <chr [1]>  2021-09-30                       NA                      1 GFF           syn21650484  In vitro viability analysis                Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
179 <chr [1]>  2021-09-30                       NA                     10 GFF           syn21650484  pRGC production stability                  Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
180 <chr [1]>  2021-09-30                       NA                     10 GFF           syn21650484  pRGC production release assay              Stem cell derived RGCs: Improving the success of transplantation strategies                                                          
181 <chr [1]>  2020-08-31                       NA                   5000 GFF           syn21641813  Readthrough                                Exploring Nonsense Suppression as a Treatment for NF1                                                                                
182 <chr [1]>  2020-08-31                       NA                   1000 GFF           syn21641813  Protein expression                         Exploring Nonsense Suppression as a Treatment for NF1                                                                                
183 <chr [1]>  2020-08-31                       NA                   1000 GFF           syn21641813  Protein expression                         Exploring Nonsense Suppression as a Treatment for NF1                                                                                
184 <chr [1]>  2020-08-31                       NA                    500 GFF           syn21641813  Protein expression                         Exploring Nonsense Suppression as a Treatment for NF1                                                                                
185 <chr [1]>  2020-08-31                       NA                    500 GFF           syn21641813  mRNA abundance                             Exploring Nonsense Suppression as a Treatment for NF1                                                                                
186 <chr [1]>  2020-08-31                       NA                     24 GFF           syn21641872  Image                                      Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type I                                                           
187 <chr [1]>  2020-08-31                       NA                     23 GFF           syn21641872  Sanger Sequencing                          Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type I                                                           
188 <chr [1]>  2020-08-31                       NA                      6 GFF           syn21641872  Image                                      Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type I                                                           
189 <chr [1]>  2020-08-31                       NA                      4 GFF           syn21641872  genomicVariants                            Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type I                                                           
190 <chr [1]>  2020-08-31                       NA                      4 GFF           syn21641872  geneExpression                             Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type I                                                           
191 <chr [1]>  2020-08-31                       NA                     20 GFF           syn21641872  Image                                      Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type I                                                           
192 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641872  Survival data                              Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type I                                                           
193 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641872  Sequence                                   Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type I                                                           
194 <chr [1]>  2021-08-30                       NA                     10 GFF           syn21641872  geneExpression                             Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type I                                                           
195 <chr [1]>  2021-08-30                       NA                      5 GFF           syn21641872  image                                      Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type I                                                           
196 <chr [1]>  2021-08-30                       NA                     NA GFF           syn21641872  image                                      Genome Editing with Engineered Vectors to Correct Neurofibromatosis Type I                                                           
197 <chr [1]>  NA                               NA                     NA GFF           syn21641876  image                                      Ataluren-promoted therapeutic nonsense suppression for neurofibromatosis                                                             
198 <chr [1]>  NA                               NA                     NA GFF           syn21641876  drugScreen                                 Ataluren-promoted therapeutic nonsense suppression for neurofibromatosis                                                             
199 <chr [1]>  NA                               NA                     NA GFF           syn21641876  image                                      Ataluren-promoted therapeutic nonsense suppression for neurofibromatosis                                                             
200 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641931  Protein Expression                         NF1 Gene Rescue in Translational Animal Models                                                                                       
201 <chr [1]>  2020-08-31                       NA                     10 GFF           syn21641931  in vivo drug response                      NF1 Gene Rescue in Translational Animal Models                                                                                       
202 <chr [1]>  2020-08-31                       NA                      8 GFF           syn21641931  in vivo drug response                      NF1 Gene Rescue in Translational Animal Models                                                                                       
203 <chr [1]>  2020-08-31                       NA                     10 GFF           syn21641931  in vivo drug response                      NF1 Gene Rescue in Translational Animal Models                                                                                       
204 <chr [1]>  2020-08-31                       NA                     10 GFF           syn21641931  Nanoparticle synthesis                     NF1 Gene Rescue in Translational Animal Models                                                                                       
205 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641931  Chemical structure                         NF1 Gene Rescue in Translational Animal Models                                                                                       
206 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641931  image                                      NF1 Gene Rescue in Translational Animal Models                                                                                       
207 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641931  Sequence                                   NF1 Gene Rescue in Translational Animal Models                                                                                       
208 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641945  geneExpression                             NF1 RNA Repair Based on Therapeutic Ribozymes                                                                                        
209 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641945  image                                      NF1 RNA Repair Based on Therapeutic Ribozymes                                                                                        
210 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641945  image                                      NF1 RNA Repair Based on Therapeutic Ribozymes                                                                                        
211 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641945  NA                                         NF1 RNA Repair Based on Therapeutic Ribozymes                                                                                        
212 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641945  image                                      NF1 RNA Repair Based on Therapeutic Ribozymes                                                                                        
213 <chr [1]>  2020-08-31                       NA                      8 GFF           syn21641955  Guides NGS counts                          Investigating Synthetic Lethality Associated with NF1 Loss                                                                           
214 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641955  drugScreen                                 Investigating Synthetic Lethality Associated with NF1 Loss                                                                           
215 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641955  NA                                         Investigating Synthetic Lethality Associated with NF1 Loss                                                                           
216 <chr [1]>  2020-07-01                       NA                    200 GFF           syn21642027  image                                      Development of Mutation Suppression Therapy in a Swine Model of NF1                                                                  
217 <chr [1]>  2020-07-01                       NA                    100 GFF           syn21642027  image                                      Development of Mutation Suppression Therapy in a Swine Model of NF1                                                                  
218 <chr [1]>  2020-07-01                       NA                     45 GFF           syn21642027  genomicVariants                            Development of Mutation Suppression Therapy in a Swine Model of NF1                                                                  
219 <chr [1]>  2020-07-01                       NA                     25 GFF           syn21642027  drugScreen                                 Development of Mutation Suppression Therapy in a Swine Model of NF1                                                                  
220 <chr [1]>  2020-07-01                       NA                      2 GFF           syn21642027  drugScreen                                 Development of Mutation Suppression Therapy in a Swine Model of NF1                                                                  
221 <chr [1]>  2020-07-01                       NA                      2 GFF           syn21642027  spreadsheet                                Development of Mutation Suppression Therapy in a Swine Model of NF1                                                                  
222 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21642010  image                                      Exon skipping to treat Neurofibromatosis Type 1 (NF1) mutations                                                                      
223 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21642010  RNA length                                 Exon skipping to treat Neurofibromatosis Type 1 (NF1) mutations                                                                      
224 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21642010  Tumor size/incidence                       Exon skipping to treat Neurofibromatosis Type 1 (NF1) mutations                                                                      
225 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21642010  GTP-Ras levels                             Exon skipping to treat Neurofibromatosis Type 1 (NF1) mutations                                                                      
226 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21642010  Sequence                                   Exon skipping to treat Neurofibromatosis Type 1 (NF1) mutations                                                                      
227 <chr [1]>  2020-08-31                       NA                     99 GFF           syn21642010  Quantification of PCR products             Exon skipping to treat Neurofibromatosis Type 1 (NF1) mutations                                                                      
228 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21642010  Sequence                                   Exon skipping to treat Neurofibromatosis Type 1 (NF1) mutations                                                                      
229 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641985  geneExpression                             AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
230 <chr [1]>  2020-08-31                       NA                     20 GFF           syn21641985  image                                      AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
231 <chr [1]>  2020-08-31                       NA                     99 GFF           syn21641985  image                                      AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
232 <chr [1]>  2020-08-31                       NA                     10 GFF           syn21641985  geneExpression                             AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
233 <chr [1]>  2020-08-31                       NA                     NA GFF           syn21641985  geneExpression                             AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
234 <chr [1]>  2020-08-31                       NA                     49 GFF           syn21641985  image                                      AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
235 <chr [1]>  2020-08-31                       NA                     49 GFF           syn21641985  image                                      AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
236 <chr [1]>  2020-08-31                       NA                     49 GFF           syn21641985  image                                      AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
237 <chr [1]>  2020-08-31                       NA                     49 GFF           syn21641985  image                                      AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
238 <chr [1]>  2020-08-31                       NA                     49 GFF           syn21641985  image                                      AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
239 <chr [1]>  2020-08-31                       NA                     49 GFF           syn21641985  image                                      AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
240 <chr [1]>  2020-08-31                       NA                     49 GFF           syn21641985  geneExpression                             AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
241 <chr [1]>  2020-08-31                       NA                     49 GFF           syn21641985  geneExpression                             AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
242 <chr [1]>  2020-08-31                       NA                     49 GFF           syn21641985  geneExpression                             AAV, Zinc Finger Protein and Antisense Oligonucleotide Strategies for Restoration of Neurofibromin Expression                        
243 <chr [1]>  2020-08-31                       NA                     49 GFF           syn21641986  geneExpression                             NA                                                                                                                                   
244 <NULL>     NA                               NA                     NA NA            syn11374354  NA                                         A 3D Cutaneous Neurofibroma Model for Automated High-Throughput Drug Screenings                                                      
245 <NULL>     NA                               NA                     NA NA            syn2343195   NA                                         Synodos NF2                                                                                                                          
246 <NULL>     NA                               NA                     NA NA            syn4939902   NA                                         A Nerve Sheath Tumor Bank from Patients with Neurofibromatosis Type 1 (NF1)                                                          
247 <NULL>     NA                               NA                     NA NA            syn8016635   NA                                         A Robust Plexiform Neurofibroma Model for Preclinical Drug Screening                                                                 
248 <NULL>     NA                               NA                     NA NA            syn4939896   NA                                         Acceptance and Commitment Training for Chronic Pain in Adolescents and Young Adults with Neurofibromatosis Type I and Plexiform Neur…
249 <NULL>     NA                               NA                     NA NA            syn4939872   NA                                         Can targeted therapy prevent neurofibroma growth in mice?                                                                            
250 <NULL>     NA                               NA                     NA NA            syn4939878   NA                                         Development of a Child Neurofibromatosis Type 1 Health Related Quality of Life Measure                                               
251 <NULL>     NA                               NA                     NA NA            syn4939876   NA                                         Combination Index Validation Studies (2 drug combinations)                                                                           
252 <NULL>     NA                               NA                     NA NA            syn4939880   NA                                         Development of a needs-based quality of life Patient Reported Outcome measure specific patients with NF1-associated pNFs             
253 <NULL>     NA                               NA                     NA NA            syn4939888   NA                                         Development of Patient Reported Outcomes System for Patients with NF1-Associated Plexiform Neurofibromas using Mixed Method Approach 
254 <NULL>     NA                               NA                     NA NA            syn4939906   NA                                         Drug Screening of pNF Cell Lines                                                                                                     
255 <NULL>     NA                               NA                     NA NA            syn11374353  NA                                         Identification of pathways triggered by Schwann cell-fibroblast interactions driving cutaneous neurofibroma growth                   
256 <NULL>     NA                               NA                     NA NA            syn11374339  NA                                         Genetic Studies of Neurofibromatosis                                                                                                 
257 <NULL>     NA                               NA                     NA NA            syn12051335  NA                                         Identifying preclinical predictors of clinical success in NF1                                                                        
258 <NULL>     NA                               NA                     NA NA            syn4939894   NA                                         Imaging Biomarkers of Neurofibromatosis Type 1-Associated Optic Pathway Glioma                                                       
259 <NULL>     NA                               NA                     NA NA            syn8016599   NA                                         Modeling signaling networks of NF1-deficient Schwann cells and plexiform neurofibromas using mass spectrometry-based proteomics      
260 <NULL>     NA                               NA                     NA NA            syn4939892   NA                                         Identification of Neurofibroma Growth and Drug Resistance Pathways                                                                   
261 <NULL>     NA                               NA                     NA NA            syn8012530   NA                                         Neurofibromatosis Type 1 Dermal Neurofibroma Longitudinal Natural History Study and Selumetinib Clinical Trial                       
262 <NULL>     NA                               NA                     NA NA            syn4984604   NA                                         Cutaneous Neurofibroma Data Resource                                                                                                 
263 <NULL>     NA                               NA                     NA NA            syn5610446   NA                                         Synodos NF1 Preclinical Models (Iowa Sanford Exemplar)                                                                               
264 <NULL>     NA                               NA                     NA NA            syn5610425   NA                                         Synodos NF1 Preclinical Models (Minnesota CCHMC Recombinetics)                                                                       
265 <NULL>     NA                               NA                     NA NA            syn5714288   NA                                         DHART SPORE Project 1: Molecular, Developmental, and Genetic Evaluation of Plexiform Neurofibromas to Inform Clinical Trials         
266 <NULL>     NA                               NA                     NA NA            syn5714289   NA                                         DHART SPORE Project 2: Targeted Therapies for Malignant Peripheral Nerve Sheath Tumors (MPNST)                                       
267 <NULL>     NA                               NA                     NA NA            syn5714290   NA                                         DHART SPORE Project 3: A High Content Clinical Trial of the MEK Inhibitor Trametinib in Juvenile Myelomonocytic Leukemia (JMML).     
268 <NULL>     NA                               NA                     NA NA            syn5714423   NA                                         DHART SPORE Project 4: Subsequent Malignant Neoplasms (SMNs) Among NF1 Cancer Survivors.                                             
269 <NULL>     NA                               NA                     NA NA            syn5698493   NA                                         Synodos NF1 Low Grade Glioma                                                                                                         
270 <NULL>     NA                               NA                     NA NA            syn6633069   NA                                         Columbia University NF1 Glioma Project                                                                                               
271 <NULL>     NA                               NA                     NA NA            syn7217946   NA                                         Development of a Novel Plexiform Neurofibroma Farming System for 96-well Plate Drug Screening                                        
272 <NULL>     NA                               NA                     NA NA            syn11681835  NA                                         Novel therapeutic development of NF1-associated malignant peripheral nerve sheath tumor (MPNST)                                      
273 <NULL>     NA                               NA                     NA NA            syn4939884   NA                                         Development of a novel treatment approach to Neurofibromatosis Type 1-related MPNST using genetically engineered Clostridium novyi-NT
274 <NULL>     NA                               NA                     NA NA            syn4939890   NA                                         Exploring the Plexiform Neurofibroma Interactome                                                                                     
275 <NULL>     NA                               NA                     NA NA            syn7217928   NA                                         Plexiform Neurofibroma Model Systems for Preclinical Drug Screening                                                                  
276 <NULL>     NA                               NA                     NA NA            syn7239560   NA                                         Evotec Drug Target Research                                                                                                          
277 <NULL>     NA                               NA                     NA NA            syn7217935   NA                                         A primary plexiform neurofibroma cell culture model for use in cell-based high-throughput screens                                    
278 <NULL>     NA                               NA                     NA NA            syn4939874   NA                                         pNF Cell Line Characterization Studies                                                                                               
279 <NULL>     NA                               NA                     NA NA            syn7239479   NA                                         Development of Plexiform Neurofibroma Cellular Assay for High-Throughput Screening                                                   
280 <NULL>     NA                               NA                     NA NA            syn7231973   NA                                         Differentiation of NF1 heterozygous and NF1 homozygous negative iPS cells into cells of the Neural Crest-Schwann cell lineage: setti…
281 <NULL>     NA                               NA                     NA NA            syn11638893  NA                                         Development of a Preclinical NF1-MPNST Platform Suitable for Precision Oncology Drug Discovery and Evaluation                        
282 <NULL>     NA                               NA                     NA NA            syn9727752   NA                                         Synodos Schwannomatosis                                                                                                              
283 <NULL>     NA                               NA                     NA NA            syn4939914   NA                                         The Role of MEK-inhibitors for the Prevention and Treatment of Optic Pathway Gliomas in an Nf1 Deficient Mouse Model                 
284 <NULL>     NA                               NA                     NA NA            syn4939904   NA                                         Regulation of GCPII for the Diagnosis and Treatment of Neurofibromas                                                                 
285 <NULL>     NA                               NA                     NA NA            syn4939916   NA                                         Screening of Plexiform Neurofibroma 3D Models                                                                                        
286 <NULL>     NA                               NA                     NA NA            syn8016577   NA                                         Search of the molecular mechanisms sustaining plexiform neurofibroma formation in a novel three-dimensional in vitro model           
287 <NULL>     NA                               NA                     NA NA            syn4939908   NA                                         Prevention trial for tumor formation in mice modeling NF1 microdeletion patients                                                     
288 <NULL>     NA                               NA                     NA NA            syn4939910   NA                                         Targeting the mechanisms underlying cutaneous neurofibroma formation in NF1: a clinical translational approach                       
289 <NULL>     NA                               NA                     NA NA            syn8012599   NA                                         Testing the Pharmacologic role of Molecular Target inhibition on Plexiform Neurofibromas in a Genetically Engineered Mouse Model tha…
290 <NULL>     NA                               NA                     NA NA            syn11672851  NA                                         Drug-Target Explorer                                                                                                                 
291 <NULL>     NA                               NA                     NA NA            syn11817821  NA                                         NF Cell Line Compound Screens                                                                                                        
292 <NULL>     NA                               NA                     NA NA            syn4939912   NA                                         The Development and Validation of PRO Measures to Assess Pain in Individuals with NF1 and pNF                                        
293 <NULL>     NA                               NA                     NA NA            syn8016650   NA                                         TRAPping the metabolic adaptations of plexiform neurofibroma                                                                         
294 <NULL>     NA                               NA                     NA NA            syn11374349  NA                                         Modeling cNF with human Schwann Cells via tunable and reversible control of NF1 protein                                              
295 <NULL>     NA                               NA                     NA NA            syn17098100  NA                                         Imaging predictors of malignant peripheral nerve sheath tumors                                                                       
296 <NULL>     NA                               NA                     NA NA            syn17100988  NA                                         The role of GABA in the working memory impairments in Neurofibromatosis Type 1                                                       
297 <NULL>     NA                               NA                     NA NA            syn5562324   NA                                         Phenotypic screening of anti-NF2 drug candidates in merlin-deficient and normal mouse Schwann cells                                  
298 <NULL>     NA                               NA                     NA NA            syn18904024  NA                                         Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1.                 
299 <NULL>     NA                               NA                     NA NA            syn21452685  NA                                         Neurofibromatosis Therapeutic Consortium - University of California, San Franciso                                                    
300 <NULL>     NA                               NA                     NA NA            syn20613866  NA                                         Neurofibromatosis Therapeutic Consortium - Brigham and Women's                                                                       
301 <NULL>     NA                               NA                     NA NA            syn22266552  NA                                         Hexokinase 2 displacement from mitochondria-associated membranes as a new antineoplastic approach in NF1-related tumors              
302 <NULL>     NA                               NA                     NA NA            syn21984813  NA                                         Predictive Modeling Utilizing a Preclinical NF1-MPNST Platform Suitable for Precision Oncology                                       
303 <NULL>     NA                               NA                     NA NA            syn23532258  NA                                         Targeting the NRG1/ErbB signaling axes for the treatment of Schwannomatosis and associated pain                                      
304 <NULL>     NA                               NA                     NA NA            syn24875850  NA                                         DNA methylation signatures in peripheral leukocytes of patients with Schwannomatosis or sporadic schwannoma                          
305 <NULL>     NA                               NA                     NA NA            syn20608511  NA                                         Whole Body MRI of NF Patients                                                                                                        
306 <NULL>     NA                               NA                     NA NA            syn25881328  NA                                         Defining the factors that dictate the pattern of glioma formation in NF1                                                             
307 <NULL>     NA                               NA                     NA NA            syn25961160  NA                                         Defining the RABL6A-YAP axis in MPNST pathogenesis and therapy                                                                       
308 <NULL>     NA                               NA                     NA NA            syn25999248  NA                                         Targeting the Let7-HMGA2 axis in Malignant Peripheral Nerve Sheath Tumor Prevention                                                  
309 <NULL>     NA                               NA                     NA NA            syn25999239  NA                                         Towards clinical translation of imaging studies in neurofibromatosis type 1                                                          
310 <NULL>     NA                               NA                     NA NA            syn25999950  NA                                         Single cell sequencing of glioma in NF1 patients                                                                                     
311 <NULL>     NA                               NA                     NA NA            syn21355225  NA                                         Evaluation of the use of antisense oligonucleotides as a personalized therapy for Neurofibromatosis Type 2 patients                  
312 <NULL>     NA                               NA                     NA NA            syn26238842  NA                                         Signaling pathways regulated by nitrated proteins as novel therapeutic targets for neurofibromatosis type 2                          
313 <NULL>     NA                               NA                     NA NA            syn26238964  NA                                         Human induced pluripotent stem cell modeling of sensory neuron-regulated NF1-deficient Schwann cell growth                           
314 <NULL>     NA                               NA                     NA NA            syn26238926  NA                                         Targeting inflammatory signaling in cutaneous neurofibromas                                                                          
315 <NULL>     NA                               NA                     NA NA            syn26241781  NA                                         Understanding how epigenetic dysregulation and Ras misactivation cooperate during NF1 deficient Schwann cell tumorigenesis to driven…
316 <NULL>     NA                               NA                     NA NA            syn26347297  NA                                         The effects of RAS signaling pathway inhibitors on tumor cells and the tumor immune microenvironment in malignant peripheral nerve s…
317 <NULL>     NA                               NA                     NA NA            syn26383473  NA                                         Exploiting cytotoxic role of nuclear Rac1 to develop targeted antitumor therapy of NF2-associated tumor                              
318 <NULL>     NA                               NA                     NA NA            syn26410510  NA                                         Neural Underpinnings of Attention in Children with NF1                                                                               
319 <NULL>     NA                               NA                     NA NA            syn26438193  NA                                         Pilot Study of Factors Impacting Medication Adherence in Children, Adolescents, and Adults with Neurofibromatosis Type 1 (NF1) on Cl…
320 <NULL>     NA                               NA                     NA NA            syn26957643  NA                                         High-Resolution Ultrasonography and Optical Frequency Domain Imaging for Measurement and Characterization of Cutaneous Neurofibromas…
321 <NULL>     NA                               NA                     NA NA            syn26966057  NA                                         Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas                                          
322 <NULL>     NA                               NA                     NA NA            syn27261816  NA                                         Evaluation of a PAK1-selective PROTAC, alone and with Hippo inhibitors, as a targeted therapy in NF2                                 
323 <NULL>     NA                               NA                     NA NA            syn27261848  NA                                         Targeting endothelial cell to macrophage communication in NF1 tumors                                                                 
324 <NULL>     NA                               NA                     NA NA            syn27261835  NA                                         Targeting combined MEK and HDAC inhibition as an effective therapeutic strategy for NF1 high-grade glioma                            
325 <NULL>     NA                               NA                     NA NA            syn27261829  NA                                         Preclinical Therapeutic Evaluation of ALY101 in a murine model of neurofibromatosis type 2                                           
326 <NULL>     NA                               NA                     NA NA            syn27762317  NA                                         Phenotype and genotype impact on plexiform neurofibroma response to MEK inhibition                                                   
327 <NULL>     NA                               NA                     NA NA            syn27761862  NA                                         Leveraging Synodos NF2 data to test novel single and combination drugs in NF2-deficient meningioma models 
jaybee84 commented 2 years ago

Hmm.. this could be because their data sharing plan specified milestone numbers 1 and 2 only, but the researchers are specifying milestone numbers 3, 4, 5 when they upload the data.

For the milestone module, we should try to capture all possible milestone numbers (in the incoming data table + in the "files" fileview).

andrewelamb commented 2 years ago

I'm a little confused. Why are researchers uploading files for milestones that don't exist?

jaybee84 commented 2 years ago

:) .. I think it is more like they did not specify these milestones in their data sharing plan early on... Its not actually their fault.. a lot of these studies are pretty old, when we did not have detailed data sharing plans asking for specific milestone association for their file uploads... So this is an issue mostly caused because we had to retrofit this functionality.

allaway commented 2 years ago

That said, it's probably important to display any milestones that we have info whether for the data or from the data sharing plans for because:

andrewelamb commented 2 years ago

I guess I'm really confused now. If the project is still ongoing why aren't the funders updating the incoming data sheet with the new milestones?

Also if the incoming data sheet doesn't have the milestone, how are supposed to know what the requirements for that milestone are?

allaway commented 2 years ago

If the project is still ongoing why aren't the funders updating the incoming data sheet with the new milestones?

The milestones are set by the scientists, generally, and they might not (often don't) communicate these changes to us or the funder, at least not on a regular basis.

Also if the incoming data sheet doesn't have the milestone, how are supposed to know what the requirements for that milestone are?

Some times they might provide data that wasn't initially planned for, ie. it's not data associated with any particular requirement. They also might promise data in milestone 1, but not provide it till milestone 4, for example. Even though this is milestone 1 data, they might report it as milestone 4.

IMO, displaying what we have on the "expected" side as well as the "real" side, regardless of whether they match, is the goal of projectLive, so that we can help untangle these types of issues. It would be nice if the "expected" and "actual" data were cleaner, but unfortunately I don't think that'll happen.